N-[(Benzyloxy)carbonyl]-L-tryptophan

Basic Information

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CAS Number

7432-21-5

Molecular Formula

C19H18N2O4

Molecular Weight

338.36 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

123.0 to 126.0 deg-C

Boiling Point

619.1℃ at 760 mmHg

Density

1.2855 (rough estimate)

Flash Point

619.1 °C at 760 mmHg

Solubility

methanol: 0.1 g/mL, clear

Refractive Index

1.6140 (estimate)

Specific Rotation

2.5 º (c=3, EtOH)

SMILES

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C1=CC=C(C=C1)COC(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)O

InChI

InChI=1S/C19H18N2O4/c22-18(23)17(10-14-11-20-16-9-5-4-8-15(14)16)21-19(24)25-12-13-6-2-1-3-7-13/h1-9,11,17,20H,10,12H2,(H,21,24)(H,22,23)/t17-/m0/s1

InChIKey

AHYFYYVVAXRMKB-KRWDZBQOSA-N

LogP

3.0900000000000016

Topological Polar Surface Area

91.42 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

464

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BDBM50043807
N-[(benzyloxy)carbonyl]-L-tryptophan
7432-21-5
Z-L-Trp-OH
M03036
(S)-2-(BENZYLOXYCARBONYLAMINO)-3-(1H-INDOL-3-YL)PROPANOIC ACID
Nalpha -benzyloxycarbonyl-L-tryptophan
EINECS 231-074-4
((Benzyloxy)carbonyl)-L-tryptophan
(S)-2-Benzyloxycarbonylamino-3-(1H-indol-3-yl)-propionic acid
Z-Trp-OH, 97%
L-Tryptophan, N-[(phenylmethoxy)carbonyl]-
N-CBZ-tryptophane
CHEMBL291603
NS00037612
N-alpha-Benzyloxycarbonyl-L-tryptophane
Cbz-L-Trp
EN300-121297
CS-W011913
N-Cbz-DL-tryptophan
MFCD00065700
Na-Cbz-L-tryptophan
(S)-N-benzyloxycarbonyl-L-tryptophan
(2S)-3-(1H-indol-3-yl)-2-(phenylmethoxycarbonylamino)propanoic acid
AS-12754
N-A-Z-L-TRYPTOPHAN
BP-13290
N(ALPHA)-CBZ-L-TRYPTOPHAN
Nalpha-benzyloxycarbonyl-L-tryptophan
AC1012
W-104421

MDL Number

MFCD00065700

Customs Code

2933990090

FAQ

What are the physical and chemical properties of N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5)?

N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5) is a white crystalline solid with a molecular weight of approximately 329.24 g/mol. It is slightly soluble in water and ethanol. The compound is known for its stability and low reactivity under normal conditions. It is used in organic synthesis as an intermediate reagent.

How is N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5) typically synthesized?

N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5) can be synthesized via the Wittig reaction followed by cyclization. The starting material is usually L-tryptophan, and the reaction typically requires a suitable solvent and appropriate conditions for high yields. The process involves the use of an organometallic reagent and is conducted with good selectivity.

What industries use N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5)?

N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various bioactive compounds. It is also utilized in the polymer industry for the development of advanced materials with specific functional properties.

What precautions should be taken when handling N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5)?

When handling N-[(Benzyloxy)carbonyl]-L-tryptophan (CAS: 7432-21-5), it is important to wear protective gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and the area should be flushed with water. Always refer to the Material Safety Data Sheet (MSDS) for specific safety measures and emergency procedures.