2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one | CAS No. 74317-53-6

2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one

Basic Information

CAS Number

74317-53-6

Molecular Formula

C28H32N4O2

Molecular Weight

456.59 g/mol

AD

Basic Physical Properties

CCN(CC)C1=CC2=C(C=C1)C3(C4=C(O2)C=C(C=C4)N(CC)CC)C5=CC=CC=C5C(=O)N3N

InChI

InChI=1S/C28H32N4O2/c1-5-30(6-2)19-13-15-23-25(17-19)34-26-18-20(31(7-3)8-4)14-16-24(26)28(23)22-12-10-9-11-21(22)27(33)32(28)29/h9-18H,5-8,29H2,1-4H3

InChIKey

WTDHTIVYKKLOTC-UHFFFAOYSA-N

LogP

5.106100000000006

Topological Polar Surface Area

62.040000000000006 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

687

Synonyms & References

English

  • 74317-53-6
  • MFCD07808762
  • AKOS024386406
  • HY-123645
  • DTXSID40400828
  • s10743
  • WTDHTIVYKKLOTC-UHFFFAOYSA-N
  • CS-0084111
  • AS-57628
  • Rhodamine B hydrazide
  • 2-amino-3',6'-bis(diethylamino)-2,3-dihydrospiro[isoindole-1,9'-xanthen]-3-one
  • 2-amino-3',6'-bis(diethylamino)spiro[isoindoline-1,9'-xanthen]-3-one
  • SCHEMBL13391001
  • 2-amino-3',6'-bis(diethylamino)spiro[isoindole-3,9'-xanthene]-1-one
  • Spiro[1H-isoindole-1,9'-[9H]xanthen]-3(2H)-one,2-amino-3',6'-bis(diethylamino)-
  • RHODAMINE B HYDRAZIDE
  • 2-amino-12,15-bis(diethylamino)spiro[isoindoline-3,9'-xanthene]-1-one
  • hydrazine rhodamine
  • N-(rhodamine-B) lactam-hydrazine
  • N-(rhodamine-B)hydrazide
  • RhB hydrazide

MDL Number

MFCD07808762

FAQ

What are the physical and chemical properties of 2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6)?

2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6) is a crystalline compound with a molecular weight of approximately 546.65 g/mol. It has good solubility in organic solvents like ethanol and acetone but is slightly soluble in water. It is moderately reactive, particularly towards nucleophilic aromatic substitution reactions. The compound is stable under normal storage conditions but should be handled under an inert atmosphere to prevent moisture absorption.

How is 2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6) typically synthesized?

2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6) is typically synthesized via a multistep process involving the coupling of diethylamine with spiro[isoindole-1,9'-xanthen]-3(2H)-one. The synthesis involves the use of a base such as sodium hydride and requires careful control of reaction temperature and time to achieve high yield and purity. The product is isolated by column chromatography and recrystallization.

What industries use 2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6)?

2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6) is used primarily in the pharmaceutical industry for its potential as a chemical intermediate. It also finds applications in the polymer industry for its ability to enhance the properties of certain polymer materials. Additionally, it is used in sensor technology and semiconductor manufacturing due to its unique molecular structure and reactivity.

What precautions should be taken when handling 2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6)?

When handling 2-Amino-3',6'-bis(diethylamino)spiro[isoindole-1,9'-xanthen]-3(2H)-one (CAS: 74317-53-6), it is crucial to use proper personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure. Spills should be carefully cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed. Safety data sheets (SDS) should be consulted for detailed emergency response procedures and storage conditions. The compound is moderately reactive, so it should be stored in a cool, dry place away from moisture and heat sources.

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