(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene | CAS No. 74311-54-9

(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene

Basic Information

CAS Number

74311-54-9

Molecular Formula

C26H22FeNP

Molecular Weight

441.34 g/mol

AD

Basic Physical Properties

CC([C]1[CH][CH][CH][C]1P(C2=CC=CC=C2)C3=CC=CC=C3)N(C)C.[CH]1[CH][CH][CH][CH]1.[Fe]

InChI

InChI=1S/C21H23NP.C5H5.Fe/c1-17(22(2)3)20-15-10-16-21(20)23(18-11-6-4-7-12-18)19-13-8-5-9-14-19;1-2-4-5-3-1;/h4-17H,1-3H3;1-5H;

InChIKey

RCAFPSZHKFOLEE-UHFFFAOYSA-N

LogP

4.821300000000004

Topological Polar Surface Area

3.24 Ų

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

337

Synonyms & References

English

  • (2S)?-1-?[(1R)?-?1-?(Dimethylamino)?ethyl]?-?2-?(diphenylphosphino)?ferrocene
  • (2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene
  • (2S)​-1-​[(1R)​-​1-​(Dimethylamino)​ethyl]​-​2-​(diphenylphosphino)​ferrocene
  • (S,R)-PPFA
  • (R)-N,N-Dimethyl-1-[(S)-2-(diphenylphosphino)ferrocenyl]ethylamine
  • (S)-N,N-Dimethyl-1-[(R)-2-(diphenylphosphino)ferrocenyl]ethylamine
  • PPFA
  • (+/-)-N,N-Dimethyl-1-[2-(diphenylphosphino)ferrocenyl]ethylamine

MDL Number

MFCD00075286

FAQ

What is (2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9)?

(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) is a chiral ferrocene derivative. It exhibits ferrocene-based catalytic properties and is characterized by its unique electronic structure, making it suitable for various organic synthesis applications.

What are the main uses of (2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9)?

(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) is primarily used as a chiral ligand in catalysis, particularly in asymmetric hydrogenation and hydroamination reactions in organic synthesis. It is also used in materials science for the development of chiral catalysts and in pharmaceutical research for the synthesis of chiral compounds.

Is (2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) safe?

(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) is generally safe when handled with proper precautions. It should be stored away from sources of ignition and heat, and exposed skin should be avoided. Protective gloves and goggles should be worn during handling to prevent eye and skin contact. In case of inhalation, seek fresh air immediately. If swallowed, do not induce vomiting and seek medical advice.

How should (2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) be stored?

(2S)-1-[(1R)-1-(Dimethylamino)ethyl]-2-(diphenylphosphino)ferrocene (CAS: 74311-54-9) should be stored in a cool, dry place, away from direct sunlight and sources of heat. It should be kept in a tightly sealed container to prevent exposure to air. The container should be made of appropriate materials that do not react with the compound. Storage at temperatures below 25°C is recommended to maintain stability.

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