3-Fluorotyrosine

Basic Information

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CAS Number

7423-96-3

Molecular Formula

C9H10FNO3

Molecular Weight

199.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

278-279 °C

Boiling Point

362.4 °C at 760 mmHg

Density

1.421

Water Solubility

Soluble in water (9.8 g/L).

Flash Point

>110°C

Refractive Index

-9 ° (C=1, 1mol/L HCl)

SMILES

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C1=CC(=C(C=C1CC(C(=O)O)N)F)O

InChI

InChI=1S/C9H10FNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1

InChIKey

VIIAUOZUUGXERI-ZETCQYMHSA-N

LogP

0.48569999999999985

Topological Polar Surface Area

83.55 Å²

Hydrogen Bond Donor/Acceptor

4 / 4

Complexity

212

Safety Information

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GHS Hazard Pictograms

H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Stability

Stable. Incompatible with strong oxidizing agents, strong reducing agents.

Synonyms & References

English

(2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
3-Fluorotyrosine, L-
PD006216
CHEBI:46534
174NRG3M2X
AKOS005258348
139-26-4
SCHEMBL274651
DB04436
(s)-3-fluorotyrosine
L-3-fluorotyrosine
VIIAUOZUUGXERI-ZETCQYMHSA-N
YOF
(2S)-2-azaniumyl-3-(3-fluoro-4-hydroxyphenyl)propanoate
Tyrosine, 3-fluoro-, L-
(s)-2-amino-3-(3-fluoro-4-hydroxy-phenyl)-propionic acid
3-fluoro-tyrosine
(s)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
L-m-Fluorotyrosine
Tyr(3-F)-OH
DS-18133
AKOS006239313
CHEMBL1236909
DTXSID10225227
CS-0157119
MFCD00002607
L-Tyrosine, 3-fluoro-
Q27095223
(S)-3-Fluorotyrsine
AM83571
3'-fluoro-l-tyrosine

MDL Number

MFCD00002607

Customs Code

2922509090

FAQ

What are the physical and chemical properties of 3-Fluorotyrosine (CAS: 7423-96-3)?

3-Fluorotyrosine (CAS: 7423-96-3) is a colorless crystalline solid with a molecular weight of approximately 189.03 g/mol. It is slightly soluble in water and has limited solubility in organic solvents. Chemically, it is reactive towards nucleophiles and can undergo easy substitution reactions. It is stable under neutral to slightly acidic conditions but can decompose at high temperatures or in strong bases.

How is 3-Fluorotyrosine (CAS: 7423-96-3) typically synthesized?

3-Fluorotyrosine (CAS: 7423-96-3) is synthesized through the fluorination of tyrosine using fluorine gas or fluorinating reagents like N-fluorobenzenesulfonimide (NFSI) in the presence of a suitable base such as triethylamine. The reaction is performed under anhydrous conditions to avoid side reactions and typically yields a high purity product with good selectivity.

What industries use 3-Fluorotyrosine (CAS: 7423-96-3)?

3-Fluorotyrosine (CAS: 7423-96-3) is primarily used in the pharmaceutical industry for the development of new drugs and as a precursor in organic synthesis. It also finds applications in polymer chemistry for the synthesis of fluorinated polymers, in sensor technology for the development of biosensors, and in semiconductor technology for the production of fluorinated materials.

What precautions should be taken when handling 3-Fluorotyrosine (CAS: 7423-96-3)?

When handling 3-Fluorotyrosine (CAS: 7423-96-3), wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Ensure proper storage in a cool, dry place away from sources of heat and ignition. In case of spill, neutralize any reactive components and follow the safety data sheet (SDS) guidelines for disposal.