rac Ketorolac | CAS No. 74103-06-3

rac Ketorolac

Basic Information

View in Editor

CAS Number

74103-06-3

Molecular Formula

C15H13NO3

Molecular Weight

255.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

160-161 ºC

Boiling Point

223.7°C at 760 mmHg

SMILES

View in Editor

OC(=O)C1CCn2c(ccc12)C(=O)c3ccccc3

InChI

InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)

InChIKey

OZWKMVRBQXNZKK-UHFFFAOYSA-N

LogP

2.2910000000000004

pKa

3.49 ±0.02(at 25℃)

Topological Polar Surface Area

59.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

376

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1(a) Class 6.1(a)

Toxicity

LD50 orally in mice: ~200 mg/kg (Rooks)

Synonyms & References

English

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Ketoralac
Ketorolac
RS37619
Acular
Dolac
Fluoxetin
KETOROLAC-D5
Lixidol
Tm-asyn
Toratex
Ketorolac trometamol for peak identification
Ketorolaco
Ketorolacum
Ketorolacum [Latin]
Ketorolaco [Spanish]
(+-)-Ketorolac
Ketorolac [INN:BAN]
RS 37619
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
Toradol (TN)
OZWKMVRBQXNZKK-UHFFFAOYSA-N
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
Macril
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 2,3-dihydro
rac Ketorolac
5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

MDL Number

MFCD00864281

FAQ

What is rac Ketorolac (CAS: 74103-06-3)?

Rac Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic and anti-inflammatory properties. Its chemical structure is a racemic mixture of (S)-Ketorolac and (R)-Ketorolac. It is commonly used in clinical settings for the short-term treatment of moderate to severe pain.

What are the main uses of rac Ketorolac (CAS: 74103-06-3)?

Rac Ketorolac is primarily used for the short-term management of moderate to severe pain in adults. It is administered intramuscularly, intravenous, or orally as needed. It is also used in some postoperative settings and for pain associated with certain medical procedures.

Is rac Ketorolac (CAS: 74103-06-3) safe?

Rac Ketorolac is generally considered safe when used as directed. However, it can cause side effects such as gastrointestinal issues, headache, dizziness, and allergic reactions. It should be used with caution in patients with a history of bleeding disorders, asthma, or renal impairment. Always follow the prescribed dosage and consult a healthcare provider if any adverse effects occur.

How should rac Ketorolac (CAS: 74103-06-3) be stored?

Rac Ketorolac should be stored at room temperature, between 15-30°C (59-86°F), in a tightly closed container to protect it from light. It should be kept away from direct sunlight and moisture. Ensure the container is sealed properly to maintain its stability and effectiveness. Avoid storing it in high humidity areas or near sources of heat.