1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid | CAS No. 74011-58-8

1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Basic Information

CAS Number

74011-58-8

Molecular Formula

C15H17FN4O3

Molecular Weight

320.32 g/mol

AD

Basic Physical Properties

Melting Point

223-229°C

Density

1.2931 (estimate)

Water Solubility

50 mg/ml in 1 M NaOHSlightly soluble in sodium hydroxide, dimethyl sulfoxide, chloroform and methanol. Insoluble in water.

CCN1C=C(C(=O)C2=CC(=C(N=C21)N3CCNCC3)F)C(=O)O

InChI

InChI=1S/C15H17FN4O3/c1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20/h7-8,17H,2-6H2,1H3,(H,22,23)

InChIKey

IDYZIJYBMGIQMJ-UHFFFAOYSA-N

LogP

0.6633000000000002

Topological Polar Surface Area

87.46 Ų

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

521

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in male, female mice, male, female rats (mg/kg): 327, 391, 236, 294 i.v.; 1237, 1320, >2000, >2000 s.c.; all >5000 orally (Senda)

Synonyms & References

English

  • Tox21_110688
  • PD107779
  • Prestwick0_000353
  • HMS3715H13
  • SBI-0051788.P002
  • NCGC00016927-06
  • EN300-122627
  • KBio2_004587
  • HMS1569G07
  • Flumark
  • FT-0630825
  • Spectrum5_001044
  • Enoxacin (Penetrex)
  • ENOXACIN [INN]
  • NSC629661
  • CAS-74011-58-8
  • MLS006011976
  • SPECTRUM1503215
  • Pharmakon1600-01503215
  • enofloxacin
  • Comprecin
  • NSC-629661
  • NCGC00016927-11
  • A837996
  • HMS3372A12
  • DTXSID5022984
  • SMP1_000113
  • C06979
  • 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro[1,8]naphthyridine-3-carboxylic acid
  • AB00052328-09
  • NCGC00016927-03

MDL Number

MFCD00133308

Customs Code

29335995

FAQ

What is 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8)?

1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8) is a complex organic compound with a molecular structure featuring a naphthyridine ring substituted with fluoro, ethyl, and piperazinyl groups. It is known for its potential applications in medicinal chemistry, particularly in the development of pharmaceutical agents.

What are the main uses of 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8)?

This compound is primarily used in pharmaceutical research for its potential therapeutic properties. It may serve as a lead compound in drug development, particularly in areas involving central nervous system disorders. Its unique structure also makes it useful in organic synthesis and chemical research for studying molecular interactions and biological activity.

Is 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8) safe?

Safety of 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8) depends on its application. In research settings, it should be handled with appropriate personal protective equipment. While it is not classified as highly toxic, long-term exposure or ingestion may pose health risks, and adherence to safety guidelines is recommended.

How should 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8) be stored?

To ensure stability, 1-Ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid (CAS: 74011-58-8) should be stored in a cool, dry place away from light. It is typically kept in a sealed container at a temperature below 25°C and in a humidity-controlled environment to prevent degradation and contamination.

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