2-Methyl-4(3H)-pyrimidinimine

Basic Information

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CAS Number

74-69-1

Molecular Formula

C5H7N3

Molecular Weight

109.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

204-205 ºC

Boiling Point

222 ºC

Density

1.155

Flash Point

111 ºC

Refractive Index

1.582

SMILES

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CC1=NC=CC(=N1)N

InChI

InChI=1S/C5H7N3/c1-4-7-3-2-5(6)8-4/h2-3H,1H3,(H2,6,7,8)

InChIKey

GKVDLTTVBNOGNJ-UHFFFAOYSA-N

LogP

0.36722

Topological Polar Surface Area

51.8 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

74.1

Synonyms & References

English

MFCD00626295
4-PYRIMIDINAMINE, 2-METHYL-
(2-methyl-pyrimidin-4-yl)-amine
AG-690/33373005
NSC-165370
J-510095
FT-0740039
SCHEMBL117690
CS-W018583
NSC165370
A865822
2-Methyl-pyrimidin-4-yl amine
AKOS030757258
2-methylpyrimidin-4-ylamine
2-methyl-4-pyrimidinamine
Q63393360
Z2092177023
GS-5845
74-69-1
AM804304
DTXSID10304309
4-Pyrimidinamine, 2-methyl- (9CI)
2-methyl-4-pyrimidinamine, AldrichCPR
4-AMINO-2-METHYLPYRIMIDINE
AKOS011055700
2-methyl-4-amino-pyrimidine
2-METHYL-4-AMINOPYRIMIDINE
CHEMBL4579021
GKVDLTTVBNOGNJ-UHFFFAOYSA-N
2-METHYL-PYRIMIDIN-4-YLAMINE
AB06587

MDL Number

MFCD00626295

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 2-Methyl-4(3H)-pyrimidinimine (CAS: 74-69-1)?

2-Methyl-4(3H)-pyrimidinimine is a crystalline solid with a molecular weight of approximately 102.11 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol. Chemically, it is highly reactive towards nucleophiles and can undergo various substitution reactions. It is used in organic synthesis due to its reactivity and ease of functionalization.

How is 2-Methyl-4(3H)-pyrimidinimine (CAS: 74-69-1) typically synthesized?

2-Methyl-4(3H)-pyrimidinimine can be synthesized via the reaction of 2-methylpyrimidin-4(3H)-one with ammonia in an aprotic solvent like acetonitrile. The reaction is catalyzed by a base such as potassium hydroxide, leading to a high yield and good selectivity. This method is commonly used in the preparation of this compound for further applications.

What industries use 2-Methyl-4(3H)-pyrimidinimine (CAS: 74-69-1)?

2-Methyl-4(3H)-pyrimidinimine is primarily used in the pharmaceutical industry for the synthesis of certain drugs due to its reactivity and ability to participate in various functional group transformations. It also finds applications in the polymer industry as a precursor for making functional polymers. Additionally, it can be used in sensor technology and semiconductor manufacturing for specific chemical reactions.

What precautions should be taken when handling 2-Methyl-4(3H)-pyrimidinimine (CAS: 74-69-1)?

When handling 2-Methyl-4(3H)-pyrimidinimine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a closed container in a cool, well-ventilated area. Spills should be handled with caution, using appropriate containment measures, and the area should be well-ventilated. In case of contact with skin or eyes, immediately flush with copious amounts of water and seek medical attention. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.