(2,4-Diaminopteridin-6-yl)methanol hydrochloride hydrate

Basic Information

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CAS Number

73978-41-3

Molecular Formula

C7H9ClN6O

Molecular Weight

228.64 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

220 °C

Boiling Point

636.5°C at 760 mmHg

Flash Point

338.8°C

SMILES

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C1=C(N=C2C(=NC(=NC2=N1)N)N)CO.Cl

InChI

InChI=1S/C7H8N6O.ClH/c8-5-4-6(13-7(9)12-5)10-1-3(2-14)11-4;/h1,14H,2H2,(H4,8,9,10,12,13);1H

InChIKey

XZHMPUJCSYVIQL-UHFFFAOYSA-N

LogP

-0.6713300000000002

Topological Polar Surface Area

124.56 Å²

Hydrogen Bond Donor/Acceptor

5 / 7

Complexity

203

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2,4-diamino-6-hydroxymethylpteridine hydrochloride
GEO-00919
2,4-diamino-6-(hydroxymethyl)-pteridine hydrochloride
(2,4-Diamino-6-pteridinyl)methanol hydrochloride
SY063959
73978-41-3
2,4-Diaminopyrimido[4,5-b]pyrazine-6-methanol monohydrochloride
AKOS005254571
PS-7744
(2,4-DIAMINOPTERIDIN-6-YL)METHANOL HCL
MFCD00191246
2,4-Diamino-6-(hydroxymethyl)pteridine hydrochloride
(2,4-diaminopteridin-6-yl)methanol;hydrochloride
(2,4-Diaminopteridin-6-yl)methanolhydrochloride
CS-W008143
BCP09302
XZHMPUJCSYVIQL-UHFFFAOYSA-N
SCHEMBL3101407
2,4-Diamino-6-(hydroxymethyl)pteridine HCl
(2,4-Diaminopteridin-6-yl)methanolhydrochloridehydrate
(2,4-Diaminopteridin-6-yl)methanol Hydrochloride; Methotrexate Imp. A (EP) as Hydrochloride; Methotrexate Impurity A as Hydrochloride
(2,4-diaminopteridin-6-yl)methanol Hydrochloride
FT-0609967
W-200498
6-Pteridinemethanol, 2,4-diamino-, monohydrochloride
(2,4-Diaminopteridin-6-yl)methanol hydrochloride
(2,4-DIAMINOPTERIDIN-6-YL)METHANOL HYDROCHLORIDE HYDRATE
2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE HYDROCHLORIDE HYDRATE
2,4-Diamino-8-(hydroxymethyl)pteridinehydrochloride
2,4-Diamino-6-(Hydroxymethyl)pteridine HCl
6-Pteridinemethanol, 2,4-diamino-, hydrochloride

MDL Number

MFCD00191246

Customs Code

2933990090

FAQ

What regulatory guidelines apply to (2,4-Diaminopteridin-6-yl)methanol hydrochloride hydrate (CAS: 73978-41-3)?

This compound is subject to regulations under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH in the EU, and FDA and EPA guidelines in the US. It is classified as a hazardous substance due to its corrosive properties, requiring appropriate labeling and handling. Detailed information on safety data sheets (SDS) and registration under REACH is essential for manufacturers and users.

Are there alternatives to (2,4-Diaminopteridin-6-yl)methanol hydrochloride hydrate (CAS: 73978-41-3) in synthesis?

There are various alternatives in the synthesis of this compound, such as using simpler amines or different diamine structures. Isomers like 4,4'-diaminodiphenylmethane or other diamine derivatives can be considered. Additionally, alternative reagents like diaminopyrimidine can serve as a starting material, providing researchers with more options depending on the specific requirements of the synthesis.

What is the market or research trend for (2,4-Diaminopteridin-6-yl)methanol hydrochloride hydrate (CAS: 73978-41-3)?

The market for this compound is driven by its application in pharmaceuticals and agriculture. Research trends focus on its use as an intermediate in drug synthesis, particularly for antiviral and anticancer compounds. Recent studies also explore its role in crop protection, indicating a growing interest in its biological activities. Price trends suggest increasing demand, with potential for further growth as novel applications are discovered.

How should waste containing (2,4-Diaminopteridin-6-yl)methanol hydrochloride hydrate (CAS: 73978-41-3) be handled?

Waste containing this compound should be collected in appropriate containers and disposed of according to local environmental and safety regulations. Incineration is a common method for disposal, provided it meets the necessary safety and emission standards. Professional waste disposal services are recommended to ensure compliance with environmental protection laws. Handling should follow strict safety protocols to prevent exposure and environmental contamination.