2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid | CAS No. 739364-95-5

2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid

Basic Information

CAS Number

739364-95-5

Molecular Formula

C8H7N3O2

Molecular Weight

177.16 g/mol

AD

Basic Physical Properties

Density

1.49±0.1 g/cm3 (20 ºC 760 Torr)

CC1=NN2C=C(C=NC2=C1)C(=O)O

InChI

InChI=1S/C8H7N3O2/c1-5-2-7-9-3-6(8(12)13)4-11(7)10-5/h2-4H,1H3,(H,12,13)

InChIKey

YHVGUXFUOSJCFJ-UHFFFAOYSA-N

LogP

0.7359199999999999

Topological Polar Surface Area

67.49000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

221

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • M2760
  • 2-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
  • SY033503
  • CS-W003908
  • 739364-95-5
  • MFCD19443280
  • AKOS022708956
  • SCHEMBL5066688
  • 2-Methyl-pyrazolo[1,5-a]pyrimidine-6-carboxylic acid
  • PB21492
  • A852234
  • SC1102
  • BCP09334
  • 2-methylpyrazolo[1,5-a]pyrimidine-6-carboxylicacid
  • EN300-1698837
  • YHVGUXFUOSJCFJ-UHFFFAOYSA-N
  • AMY9287
  • FT-0722862
  • DS-8624
  • DTXSID40630527
  • 2-Methylpyrazolo[1,5-a]pyriMidine-6-carboxylic acid
  • 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylicacid(PPCA)
  • QC-3758
  • AK164570
  • 5592AJ
  • TRA0073405
  • LS40897
  • FCH1133845
  • OR306578
  • AB0088167

MDL Number

MFCD19443280

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS: 739364-95-5)?

2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid is a crystalline solid with a molecular weight of approximately 220.21 g/mol. It has a high solubility in polar solvents like DMSO and moderate solubility in water. The compound is moderately reactive, showing basic properties and can undergo acid-base reactions. It decomposes above 200°C.

How is 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS: 739364-95-5) typically synthesized?

2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid is commonly synthesized via the condensation of 2-methylpyrazole and 6-carboxy-1H-pyrimidine-4-one. Catalysts like p-toluenesulfonic acid (p-TSA) are used to promote the reaction. The yield is typically around 70-80%, with good selectivity towards the desired product.

What industries use 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS: 739364-95-5)?

2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid finds applications in pharmaceuticals, where it is used as an intermediate for drug synthesis. It is also utilized in the preparation of polymers and as a component in sensors and semiconductor materials due to its electronic properties.

What precautions should be taken when handling 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS: 739364-95-5)?

When handling 2-Methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled in a fume hood. For more detailed safety information, refer to the Safety Data Sheet (SDS).

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