(5-Chloro-3-thienyl)methanol

Basic Information

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CAS Number

73919-87-6

Molecular Formula

C5H5ClOS

Molecular Weight

148.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=C(SC=C1CO)Cl

InChI

InChI=1S/C5H5ClOS/c6-5-1-4(2-7)3-8-5/h1,3,7H,2H2

InChIKey

RJCDMSXITBOXRL-UHFFFAOYSA-N

LogP

1.8938

Topological Polar Surface Area

20.23 Å²

Hydrogen Bond Donor/Acceptor

1 / 1

Complexity

78.8

Synonyms & References

English

AKOS016002231
3-Thiophenemethanol, 5-chloro-
MFCD13659394
EN300-1965616
PB13604
AS-33768
(5-CHLOROTHIOPHEN-3-YL)METHANOL
DTXSID30608851
73919-87-6
SCHEMBL1196640
CS-0053150
(5-chloro-3-thienyl)methanol
YCA91987
5-CHLOROTHIOPHENE-3-METHANOL
FT-0686479
RJCDMSXITBOXRL-UHFFFAOYSA-N
(5-Chlorothiophen-3-yl)methanol
5-chloro-3-Thiophenemethanol
5-Chlorothiophene-3-methanol
(5-chlorothien-3-yl)methanol
3-Thiophenemethanol,5-chloro
RW2811
(5-chlorothiophen-3-yl)methanol

MDL Number

MFCD13659394

Customs Code

2934999090

FAQ

What are the physical and chemical properties of (5-Chloro-3-thienyl)methanol (CAS: 73919-87-6)?

(5-Chloro-3-thienyl)methanol is a colorless liquid with a molecular weight of approximately 149.57 g/mol. It has a boiling point of around 155°C and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo substitution reactions. It also shows reactivity towards acids and bases, making it suitable for various chemical transformations.

How is (5-Chloro-3-thienyl)methanol (CAS: 73919-87-6) typically synthesized?

(5-Chloro-3-thienyl)methanol is commonly synthesized via the reaction of 3-thiophenecarboxaldehyde with chloromethyl ketone in the presence of sodium hydroxide. The reaction yields good selectivity and a reasonable yield, making it a suitable method for industrial production.

What industries use (5-Chloro-3-thienyl)methanol (CAS: 73919-87-6)?

(5-Chloro-3-thienyl)methanol finds applications in the pharmaceutical industry for the synthesis of certain medications, as well as in the polymer industry for the development of advanced materials. It is also utilized in the production of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling (5-Chloro-3-thienyl)methanol (CAS: 73919-87-6)?

When handling (5-Chloro-3-thienyl)methanol, it is crucial to use appropriate personal protective equipment (PPE), such as gloves, safety glasses, and a lab coat. The compound should be stored in a fume hood or a well-ventilated area. In case of a spill, avoid contact with skin and eyes, and dispose of the spill according to the Material Safety Data Sheet (MSDS). Always refer to the latest SDS for specific handling guidelines.