(5-Chloro-3-thienyl)methanol(CAS: 73919-87-6)

(5-Chloro-3-thienyl)methanol is a colorless liquid with a molecular weight of approximately 149.57 g/mol. It has a boiling point of around 155°C and is slightly soluble in water. The compound is reactive towards nucleophiles and can undergo substitution reactions. It also shows reactivity towards acids and bases, making it suitable for various chemical transformations.

(5-Chloro-3-thienyl)methanol is commonly synthesized via the reaction of 3-thiophenecarboxaldehyde with chloromethyl ketone in the presence of sodium hydroxide. The reaction yields good selectivity and a reasonable yield, making it a suitable method for industrial production.

(5-Chloro-3-thienyl)methanol finds applications in the pharmaceutical industry for the synthesis of certain medications, as well as in the polymer industry for the development of advanced materials. It is also utilized in the production of sensors and semiconductors due to its unique chemical properties.

When handling (5-Chloro-3-thienyl)methanol, it is crucial to use appropriate personal protective equipment (PPE), such as gloves, safety glasses, and a lab coat. The compound should be stored in a fume hood or a well-ventilated area. In case of a spill, avoid contact with skin and eyes, and dispose of the spill according to the Material Safety Data Sheet (MSDS). Always refer to the latest SDS for specific handling guidelines.