2-Chloro-3-quinolinecarbaldehyde

Basic Information

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CAS Number

73568-25-9

Molecular Formula

C10H6ClNO

Molecular Weight

191.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

Melting Point

148-150 °C

Density

1.364

SMILES

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C1=CC=C2C(=C1)C=C(C(=N2)Cl)C=O

InChI

InChI=1S/C10H6ClNO/c11-10-8(6-13)5-7-3-1-2-4-9(7)12-10/h1-6H

InChIKey

SDKQWXCBSNMYBN-UHFFFAOYSA-N

LogP

2.7007000000000003

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

197

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

CS-W015838
2-chloro-quinoline-3-carbaldehyde
2-chloro-3-formylquinoline
SDKQWXCBSNMYBN-UHFFFAOYSA-N
AKOS000100788
2-chloroquinolin-3-carbaldehyde
2-chloro-3-quinolinecarbaldehyde
SB67455
InChI=1/C10H6ClNO/c11-10-8(6-13)5-7-3-1-2-4-9(7)12-10/h1-6
DTXSID80351108
AM20070151
2-Chloroquinoline-3-carboxaldehyde
Z56899135
A837856
2-chloro-3-quinoline carboxaldehyde
F0010-0600
2-Chloro-3-quinolinecarboxaldehyde
BB 0258201
SCHEMBL372264
2-Chloro-3-quinolinecarboxaldehyde, 98%
2-chloro-quinoline-3-carboxaldehyde
FT-0611656
EN300-17224
73568-25-9
2-chloroquinoline-3-carbaldehyde
3-Quinolinecarboxaldehyde, 2-chloro-
DS-13206
CHEMBL4528828
C2289
BP-12764
2-Chloroquinoline-3-carbaldehyde

MDL Number

MFCD00130079

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9)?

2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9) is a yellow solid with a molecular weight of approximately 213.66 g/mol. It has a melting point of 145-147°C and is soluble in organic solvents such as methanol and ethanol. This compound is highly reactive and prone to dehydrohalogenation and condensation reactions.

How is 2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9) typically synthesized?

2-Chloro-3-quinolinecarbaldehyde is typically synthesized via the condensation of chlorobenzaldehyde with 3-quinolinecarboxaldehyde using concentrated hydrochloric acid as a catalyst. The reaction yields a mixture of products, with the desired compound being isolated by recrystallization or other purification methods.

What industries use 2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9)?

2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9) is used in the pharmaceutical industry for the synthesis of various bioactive molecules. It also finds applications in the sensor technology sector due to its reactivity and ability to undergo specific chemical transformations.

What precautions should be taken when handling 2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9)?

When handling 2-Chloro-3-quinolinecarbaldehyde (CAS: 73568-25-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials, and the area should be appropriately ventilated. Always refer to the Safety Data Sheet (SDS) for complete handling guidelines.