Propiolamide | CAS No. 7341-96-0

Propiolamide

Basic Information

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CAS Number

7341-96-0

Molecular Formula

C3H3NO

Molecular Weight

59.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

57-62 °C

Boiling Point

134.6±23.0 °C at 760 mmHg

Density

1.1±0.1 g/cm3

Flash Point

35.2±22.6 °C

Refractive Index

1.465

Vapor Pressure

8.0±0.2 mmHg at 25°C

SMILES

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C#CC(=O)N

InChI

InChI=1S/C2H5NO/c1-2(3)4/h1H3,(H2,3,4)

InChIKey

DLFVBJFMPXGRIB-UHFFFAOYSA-N

LogP

-0.5084000000000002

Topological Polar Surface Area

43.09 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

86.3

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

UNII-KW3KN5TM5F
propynoic acid amide, AldrichCPR
SY060790
NSC-520954
FT-0600128
FT-0674068
BL007595
HC.equiv.CCONH2
Propiolamide
AM20100705
EN300-61937
propiolic acid amide
Propynamide
propargylamide
HC.$.CCONH2
prop-2-ynamide
MFCD04035573
DTXSID50223641
2-Propynamide
NSC 520954
PD118606
NSC520954
7341-96-0
A21104
CHEBI:51764
PROPYNOIC ACID AMIDE
KW3KN5TM5F
J-524058
MB03070
Q27122735
AKOS006237140

MDL Number

MFCD04035573

FAQ

What are the physical and chemical properties of Propiolamide (CAS: 7341-96-0)?

Propiolamide is a colorless, crystalline solid with a molecular weight of approximately 82.06 g/mol. It has a pKa of about 14.2. It is sparingly soluble in water and soluble in most organic solvents. Chemically, it is relatively stable but can react with strong acids and bases. It is used in the synthesis of other compounds and as a reagent in organic chemistry.

How is Propiolamide (CAS: 7341-96-0) typically synthesized?

Propiolamide can be synthesized by the amidation of propionic acid with ammonia or an amine. A common method involves reacting propionic acid with ammonia to form the amide. The reaction typically requires a dehydrating agent to facilitate the amidation process. The yield is moderate, and the purity can be increased through recrystallization.

What industries use Propiolamide (CAS: 7341-96-0)?

Propiolamide is used primarily in the pharmaceutical and chemical industries. It serves as a versatile reagent in the synthesis of various compounds, including pharmaceuticals and polymers. It is also utilized in the preparation of other chemical intermediates and in the development of new materials.

What precautions should be taken when handling Propiolamide (CAS: 7341-96-0)?

When handling propiolamide, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be handled in a well-ventilated area or with the use of a fume hood. Spills should be cleaned up immediately with caution, and the site should be well rinsed. Safety data sheets (SDS) should be consulted for detailed safety information and emergency procedures.