3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine

Basic Information

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CAS Number

73259-81-1

Molecular Formula

C8H16N2O4

Molecular Weight

204.23 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

210 °C (dec.)

Boiling Point

364.4 °C at 760 mmHg

Density

1.1890

Flash Point

174.2 °C

Refractive Index

1.488

Specific Rotation

-5.5 º (c=1, acetic acid)

SMILES

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CC(C)(C)OC(=O)NC(CN)C(=O)O

InChI

InChI=1S/C8H16N2O4/c1-8(2,3)14-7(13)10-5(4-9)6(11)12/h5H,4,9H2,1-3H3,(H,10,13)(H,11,12)/t5-/m0/s1

InChIKey

KRJLRVZLNABMAT-YFKPBYRVSA-N

LogP

-0.07699999999999907

Topological Polar Surface Area

101.64999999999999 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

222

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N-ALPHA-T-BUTYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID
N-Boc-L-2,3-diaminopropanoic acid
HY-W008325
(2S)-2-(tert-butyloxycarbonylamino)-3-aminopropionic acid
SCHEMBL646750
(s)-3-amino-2-boc-aminopropanoic acid
AC-5655
(S)-2-tert-Butoxycarbonylamino-3-amino-propionic acid
73259-81-1
(S)-3-Amino-2-tert-butoxycarbonylamino-propionic acid
GS-6687
EN300-246237
(2S)-3-amino-2-{[(tert-butoxy)carbonyl]amino}propanoic acid
Boc-Dap-OH
N(alpha)-boc-L-2,3-diaminopropionic acid
(2S)-2-tert-Butoxycarbonylamino-3-aminopropionic acid
(S)-3-Amino-2-(tert-butoxycarbonylamino)propionic Acid
3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine
Boc-L-Dap
3-amino-N-[(1,1-dimethylethoxy)carbonyl]-L-alanine
KRJLRVZLNABMAT-YFKPBYRVSA-N
N-Boc-beta-amino-L-alanine
(S)-3-amino-2-tert-butoxycarbonylamino propionic acid
(S)-3-Amino-2-((tert-butoxycarbonyl)amino)propanoic acid
AKOS007930034
(N-Boc-beta-amino)-Ala-OH
(2S)-3-azaniumyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoate
MFCD00236843
BOC-L-DAP-OH
CS-W008325
Alanine, 3-amino-N-[(1,1-dimethylethoxy)carbonyl]-

MDL Number

MFCD00236843

FAQ

What are the physical and chemical properties of 3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine (CAS: 73259-81-1)?

3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine is a white crystalline powder with a molecular weight of approximately 277.37 g/mol. It has a high solubility in water and ethanol but is relatively insoluble in organic solvents. Chemically, it is highly reactive, particularly with bases and reducing agents, making it susceptible to hydrolysis and reduction.

How is 3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine (CAS: 73259-81-1) typically synthesized?

3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine is typically synthesized via a multi-step peptide synthesis route, involving the condensation of L-alanine and 2-methyl-2-propanol followed by a protecting group strategy. Commonly, a solid-phase synthesis approach is used, employing Fmoc chemistry, with appropriate deprotection and coupling steps to achieve high yields and selectivity.

What industries use 3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine (CAS: 73259-81-1)?

3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine is primarily used in the pharmaceutical industry for the synthesis of complex peptides and protein therapeutics. It is also utilized in the polymer industry for the modification of polymers and in the sensor industry for the development of chemical and biological sensors.

What precautions should be taken when handling 3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine (CAS: 73259-81-1)?

When handling 3-Amino-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-alanine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly rinsed with water. Always refer to the SDS for detailed safety information and procedures.