2,2-Dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]-2-propanyl}acetamide | CAS No. 73231-34-2

2,2-Dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]-2-propanyl}acetamide

Basic Information

CAS Number

73231-34-2

Molecular Formula

C12H14Cl2FNO4S

Molecular Weight

358.22 g/mol

AD

Basic Physical Properties

Melting Point

153.0 to 157.0 deg-C

Boiling Point

618℃

Density

1.5±0.1 g/cm3

Flash Point

>110°(230°F)

Solubility

Soluble in ethanol to 25mM and in DMSO to 100mM

Refractive Index

1.548

Specific Rotation

-16° to -19° (c=1, DMF)

CS(=O)(=O)C1=CC=C(C=C1)C(C(CF)NC(=O)C(Cl)Cl)O

InChI

InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

InChIKey

AYIRNRDRBQJXIF-NXEZZACHSA-N

LogP

1.3815

Topological Polar Surface Area

83.47 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

447

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • s4201
  • 2,2-dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methanesulfonylphenyl)propan-2-yl]acetamide
  • BRD-K11298197-001-03-9
  • D-(-)-threo-2-Dichloroacetamido-3-fluoro-1-(4-methylsulfonylphenyl)-1-propanol
  • Prestwick3_000955
  • FLORFENICOL (EMA EPAR VETERINARY)
  • NSC 759287
  • UNII-9J97307Y1H
  • F0811
  • (1R,2S)-2-dichloroacetamido-3-fluoro-1-[4-(methylsulfonyl)phenyl]-1-propanol
  • Z2065671685
  • Nuflor gold
  • SCHEMBL49425
  • CHEBI:87185
  • Benzenesulfonic acid, 4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-, methyl ester, (R-(R*,S*))-
  • Florvio 2.3% Concentrate Solution
  • SMR001233384
  • chloramphen
  • AB00513976
  • D-threo-2,2-Dichloro-N-(alpha-(fluoromethyl)-beta-hydroxy-p-(methylsulfonyl)phenethyl)acetamide
  • Nuflor (TN)
  • CHEMBL1241590
  • 9J97307Y1H
  • D04194
  • Norfenicol
  • HMS3714P12
  • 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
  • AYIRNRDRBQJXIF-NXEZZACHSA-N
  • Florfenicol, analytical standard, for drug analysis
  • 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)-2-propyl]acetamide
  • GTPL12923

MDL Number

MFCD00864834

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