2-Pyridinethiol

Basic Information

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CAS Number

73018-10-7

Molecular Formula

C5H5NS

Molecular Weight

111.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

127-130 °C

Boiling Point

194 ºC

Density

1.166

Flash Point

71 ºC

Refractive Index

1.653

SMILES

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C1=CC(=S)NC=C1

InChI

InChI=1S/C5H5NS/c7-5-3-1-2-4-6-5/h1-4H,(H,6,7)

InChIKey

WHMDPDGBKYUEMW-UHFFFAOYSA-N

LogP

1.3702999999999999

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

135

Synonyms & References

English

(2S,3S)-3-Amino-2-methyl-4-oxo-1-azetidinesulfonicacid
Pyridin-2(1H)-thione
SCHEMBL54576
PD007080
SY009099
2-Pyridinethiol; 2-Pyridinethione; 2-Pyridyl mercaptan; 2-Pyridylthiol; 2-Sulfanylpyridine
J-524119
UNII-EE982KT952
2-mercaptopyridine (thione form)
2-Mercaptopyridine, ReagentPlus(R), 99%
pyridine-2(1H)-thione
Pyridinethione
FT-0698903
Pyrid-2-thione
2-Thiopyridone
EINECS 220-131-9
CHEBI:45223
AKOS000120194
MERCAPTOPYRIDINE, 2-
CS-0020126
2637-34-5;2-Pyridinethiol;Pyridine-2-thiol;2-Thiopyridine
Thiopyridone-2 [French]
EINECS 249-657-7
thioxopyridine
F9995-0226
I+/--Thiopyridon
Pyridine-2-thiol
2-Mercapto pyridine
Thiopyridone-2
NSC41337
E81838

MDL Number

MFCD00006285

FAQ

What are the physical and chemical properties of 2-Pyridinethiol (CAS: 73018-10-7)?

2-Pyridinethiol is a yellow solid with a crystalline form. Its molecular weight is approximately 123.18 g/mol. It has a low solubility in water but is soluble in organic solvents such as ethanol and acetone. It is reactive towards oxidizing agents and can form coordination complexes with metal ions. This compound is also known for its use in biosensors and as a ligand in coordination chemistry.

How is 2-Pyridinethiol (CAS: 73018-10-7) typically synthesized?

2-Pyridinethiol is typically synthesized by the thiolation of pyridine using a reducing agent like sodium borohydride. This process yields a high yield and is selective. Other methods involve the reaction of pyridine with thiols or thioacetals under controlled conditions.

What industries use 2-Pyridinethiol (CAS: 73018-10-7)?

2-Pyridinethiol is used in various industries. It is a key component in the development of biosensors and is also used in the synthesis of metal-organic frameworks (MOFs) for gas storage. Additionally, it has applications in the pharmaceutical industry as a ligand and in semiconductor technology for doping purposes.

What precautions should be taken when handling 2-Pyridinethiol (CAS: 73018-10-7)?

When handling 2-Pyridinethiol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Handle in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbents, and the area should be rinsed with water. Refer to the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.