5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine

Basic Information

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CAS Number

73-66-5

Molecular Formula

C8H13N3O

Molecular Weight

167.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

295.79°C (rough estimate)

Density

1.1283 (rough estimate)

Refractive Index

1.6500 (estimate)

SMILES

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CCOCC1=CN=C(N=C1N)C

InChI

InChI=1S/C8H13N3O/c1-3-12-5-7-4-10-6(2)11-8(7)9/h4H,3,5H2,1-2H3,(H2,9,10,11)

InChIKey

KEYFHYRXUHGMLW-UHFFFAOYSA-N

LogP

0.9037200000000001

Topological Polar Surface Area

61.03 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

132

Synonyms & References

English

5-(ethoxymethyl)-2-methylpyrimidin-4-amine
SCHEMBL7724215
NS00037543
Q27282705
NSC 41790
5-Ethoxymethyl-2-methylpyrimidin-4-ylamine
NSC41790
5-25-13-00059 (Beilstein Handbook Reference)
AKOS001325869
BRN 0139361
5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine
2-METHYL-4-AMINO-5-(ETHOXYMETHYL)PYRIMIDINE
2-Methyl-4-amino-5-ethoxymethylpyrimidine
4-Pyrimidinamine, 5-(ethoxymethyl)-2-methyl-
CS-0088121
SR-01000513060-1
73-66-5
UNII-L4R9O0B5C5
NSC-41790
D74667
4-Amino-5-(ethoxymethyl)-2-methylpyrimidine
DTXSID20223274
4-Amino-5-ethoxymethyl-2-methylpyrimidine
Z234853588
Oprea1_408005
2-Methyl-5-(ethoxymethyl)-6-aminopyrimidine
BS-3046
L4R9O0B5C5
MFCD00223754
SB56543
Pyrimidine, 4-amino-5-(ethoxymethyl)-2-methyl-

MDL Number

MFCD00223754

Customs Code

2933599090

FAQ

What are the physical and chemical properties of 5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5)?

5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5) is a white crystalline solid with a molecular weight of 165.18 g/mol. It has a melting point of 158-160°C and is slightly soluble in water. It is stable in air and light but reacts with strong acids and bases. It is an important intermediate in pharmaceutical and agrochemical synthesis.

How is 5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5) typically synthesized?

5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5) is typically synthesized through the reaction of 2-methyl-4-pyrimidinamine with ethyl acetoacetate in the presence of a catalytic amount of sodium hydroxide. This method provides high selectivity and good yield.

What industries use 5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5)?

5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5) is used in the pharmaceutical industry for the synthesis of various drugs and in the agrochemical industry for developing new herbicides and pesticides. It is also used in the polymer industry for the production of specialty polymers.

What precautions should be taken when handling 5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5)?

When handling 5-(Ethoxymethyl)-2-methyl-4-pyrimidinamine (CAS: 73-66-5), wear protective equipment such as gloves and safety goggles. Work in a well-ventilated area or a fume hood. Dispose of waste materials according to local regulations. Refer to the safety data sheet (SDS) for detailed information on handling and storage.