Bendroflumethiazide

Basic Information

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CAS Number

73-48-3

Molecular Formula

C15H14F3N3O4S2

Molecular Weight

421.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

205-207°C

Density

1.4711 (estimate)

Solubility

DMSO (Slightly), Methanol (Slightly)

SMILES

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C1=CC=C(C=C1)CC2NC3=C(C=C(C(=C3)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N2

InChI

InChI=1S/C15H14F3N3O4S2/c16-15(17,18)10-7-11-13(8-12(10)26(19,22)23)27(24,25)21-14(20-11)6-9-4-2-1-3-5-9/h1-5,7-8,14,20-21H,6H2,(H2,19,22,23)

InChIKey

HDWIHXWEUNVBIY-UHFFFAOYSA-N

LogP

1.6253999999999993

Topological Polar Surface Area

118.36 Å²

Hydrogen Bond Donor/Acceptor

4 / 7

Complexity

740

Synonyms & References

English

Bendroflumethiazide, British Pharmacopoeia (BP) Reference Standard
HMS2230G10
3-Benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4- benzothiadiazine-7-sulfonamide
Salures
4-27-00-08041 (Beilstein Handbook Reference)
NCGC00089729-02
BENDROFLUMETHIAZIDE [WHO-DD]
Q1169164
Nikion
Rautrax N
FT-0662519
+/--3-benzyl-3,4-dihydro-6-(trifluoromethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
BENDROFLUMETHIAZIDE (MART.)
Bristuric
SCHEMBL26016
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3,4-dihydro-3-(phenylmethyl)-6-(trifluoromethyl)-, 1,1-dioxide
CORZIDE COMPONENT BENDROFLUMETHIAZIDE
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 3-benzyl-3,4-dihydro-6-(trifluoromethyl)-, 1,1-dioxide
HMS2092J16
BENDROFLUMETHIAZIDE [USP-RS]
Relan .beta.
HMS1570M10
KBio2_004434
Benzy-rodiuran
HMS2097M10
Flumersil
BENDROFLUMETHIAZIDE [USP MONOGRAPH]
NSC-758229
Repicin
Naigaril
Flumesil

MDL Number

MFCD00078963

FAQ

What is Bendroflumethiazide (CAS: 73-48-3)?

Bendroflumethiazide is a thiazide diuretic used to treat hypertension and edema. It is a white or practically white crystalline powder with a molecular formula of C14H14N2O4S and a molecular weight of 314.36.

What are the main uses of Bendroflumethiazide (CAS: 73-48-3)?

Bendroflumethiazide is primarily used as a diuretic to manage hypertension and edema. It helps to reduce blood pressure and eliminate excess fluid from the body, making it effective in treating heart failure and kidney diseases.

Is Bendroflumethiazide (CAS: 73-48-3) safe?

Bendroflumethiazide is generally safe when used as directed. However, it can cause side effects such as electrolyte imbalance and hyperglycemia. It is important to follow the prescribed dosage and monitor for any adverse reactions.

How should Bendroflumethiazide (CAS: 73-48-3) be stored?

Bendroflumethiazide should be stored in a tightly closed container at room temperature (15-30°C), protected from light and moisture. It should be kept out of reach of children and away from direct sunlight and heat sources.