(3R)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid

Basic Information

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CAS Number

72925-16-7

Molecular Formula

C10H17NO4

Molecular Weight

215.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

138-143 °C

Boiling Point

337.2℃ at 760 mmHg

Density

1.201

Flash Point

157.7℃

Solubility

Soluble in Dimethyl sulfoxide (DMSO).

Refractive Index

1.502

Specific Rotation

-15 ~ -11° (c=0.5, chloroform)

SMILES

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CC(C)(C)OC(=O)N1CCC(C1)C(=O)O

InChI

InChI=1S/C10H17NO4/c1-10(2,3)15-9(14)11-5-4-7(6-11)8(12)13/h7H,4-6H2,1-3H3,(H,12,13)/t7-/m1/s1

InChIKey

HRMRQBJUFWFQLX-SSDOTTSWSA-N

LogP

1.328

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

269

Safety Information

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GHS Hazard Pictograms

H400

Hazard Statement

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Synonyms & References

English

(R)-Pyrrolidine-1,3-dicarboxylic acid tert butyl ester
(R)-N-Boc-pyrroldine-3-carboxylic acid
72925-16-7
SCHEMBL42957
(R)-1-BOC-3-PYRROLIDINECARBOXYLIC ACID
(r)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester
BCP26652
(r)-1-n-boc-pyrrolidine-3-carboxylic acid
1-(tert-butoxycarbonyl)pyrrolidine-3(R)-carboxylic acid
(r)-1-boc-3-carboxyl pyrrolidine
EN300-159829
(R)-1-N-Boc-beta-proline
DTXSID00363687
(R)-1-tert-butoxycarbonyl-pyrrolidine-3-carboxylic acid
AM804292
AC-2238
(R)-1-(TERT-BUTOXYCARBONYL)-3-PYRROLIDINECARBOXYLIC ACID
(s)-1-n-boc-pyrrolidine-3-carboxylic acid
AKOS005258705
(3R)-1-(TERT-BUTOXYCARBONYL)-3-PYRROLIDINECARBOXYLIC ACID
(3r)-1-(tert-butoxycarbonyl)pyrrolidine-3-carboxylic acid
F8887-8314
(3R)-1-[(tert-butoxy)carbonyl]pyrrolidine-3-carboxylic acid
(3R)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acid
A4419
N-BOC-D-BETA-PROLINE
HRMRQBJUFWFQLX-SSDOTTSWSA-N
(R)-1-Boc-pyrrolidine-3-carboxylic acid
AKOS005145920
MFCD03094727
(r)-n-boc-pyrrolidine-3-carboxylic acid

MDL Number

MFCD03094727

FAQ

What regulatory guidelines apply to (3R)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid (CAS: 72925-16-7)?

This compound falls under the classification of REACH regulations in the European Union, which mandates registration, evaluation, authorization, and restriction of chemicals. It also complies with GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for hazardous substances, requiring appropriate hazard communication. In the USA, it should adhere to FDA and EPA guidelines for chemical handling and disposal to ensure safety and environmental protection.

Are there alternatives to (3R)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid (CAS: 72925-16-7) in synthesis?

Several alternatives can be used in its synthesis, such as (3S)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid or similar isomers. Common alternative reagents include other carboxylic acids or hydroxylic compounds that can achieve similar functional groups without the specific stereochemistry of the given compound.

What is the market or research trend for (3R)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid (CAS: 72925-16-7)?

There is growing interest in this compound due to its potential in pharmaceuticals and pharmaceutical intermediates. Market trends suggest increasing research in its application for drug synthesis, particularly in areas like anti-inflammatory and anti-tumor agents. Research is also exploring its use in cosmetics and as a food additive.

How should waste containing (3R)-1-{[(2-Methyl-2-propanyl)oxy]carbonyl}-3-pyrrolidinecarboxylic acid (CAS: 72925-16-7) be handled?

Waste containing this compound should be collected in appropriate containers and stored in a well-ventilated area away from sources of ignition. Proper incineration or professional waste disposal services should be utilized for final disposal. Environmental precautions include ensuring the waste does not contaminate soil or water sources. Disposal methods should comply with local and international regulations to prevent environmental harm.