5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine

Basic Information

View in Editor

CAS Number

7288-28-0

Molecular Formula

C11H22N2O2Si2

Molecular Weight

270.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

73-75 °C

Boiling Point

127-130 °C/18 mmHg

SMILES

View in Editor

CC1=CN=C(N=C1O[Si](C)(C)C)O[Si](C)(C)C

InChI

InChI=1S/C11H22N2O2Si2/c1-9-8-12-11(15-17(5,6)7)13-10(9)14-16(2,3)4/h8H,1-7H3

InChIKey

DRNUNECHVNIYHQ-UHFFFAOYSA-N

LogP

3.2124200000000016

Topological Polar Surface Area

44.24000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

251

Synonyms & References

English

o,o-bis(trimethylsilyl)thymine
trimethyl-(5-methyl-2-trimethylsilyloxypyrimidin-4-yl)oxysilane
5-methyl-2,4-bis[( trimethylsilyl)oxy ]pyrimidine
NSC-154616
Pyrimidine, 5-methyl-2,4-bis[(trimethylsilyl)oxy]-
O,O'-Bis(trimethylsilyl)thymine, 97%
5-methyl-2,4-bis(trimethylsilyloxy)pyrimidine
7288-28-0
Pyrimidine, 5-methyl-2,4-bis((trimethylsilyl)oxy)-
W28V4H6YE4
Thymine, bis-TMS
O,O'-Bis(trimethylsilyl)thymine
2,4-Bis(trimethylsilyl)thymine
Pyrimidine, 2,4-dihydroxy-5-methyl, bis-TMS
5-Methyl-2,4-bis((trimethylsilyl)oxy)pyrimidine
Bis(O-trimethylsilyl)thymine
MFCD00053571
NSC 154616
AKOS024319173
5-Methyl-2,4-bis(trimethylsiloxy)pyrimidine
SCHEMBL1335976
5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine
NSC154616
DTXSID1064615
Pyrimidine, 5-methyl-2,4-bis(trimethylsiloxy)-
Pyrimidine,5-methyl-2,4-bis[(trimethylsilyl)oxy]-
O,O′-Bis(trimethylsilyl)thymine
O,O-Bis(Trimethylsilyl)Thymin
0,0-Bis (trimethylsilyl)thymine
O,O'-bis-TMS-thymine

MDL Number

MFCD00053571

FAQ

What regulatory guidelines apply to 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0)?

5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) falls under the scope of various regulatory guidelines. It should comply with the Globally Harmonized System (GHS) of Classification and Labelling of Chemicals, which includes handling, storage, and disposal guidelines. Additionally, manufacturers and importers must adhere to REACH regulations in the European Union, ensuring that the chemical is safe for its intended uses. In the United States, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) may also have specific requirements for its use and disposal.

Are there alternatives to 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) in synthesis?

While 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) is a specific compound used in certain chemical syntheses, there are alternative reagents that can be employed. For example, similar functional groups can be found in other silylated pyrimidines or related heterocycles. The choice of alternative reagents depends on the specific requirements of the synthesis, such as reactivity, availability, and cost.

What is the market or research trend for 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0)?

The market for 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) is driven by its use in organic synthesis, particularly in the preparation of other silylated compounds. Research trends indicate a growing interest in the development of new silyl protecting groups and their application in various chemical reactions. The increasing demand in pharmaceutical and agrochemical industries, coupled with advancements in synthetic methodologies, suggests a positive market outlook for this compound.

How should waste containing 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) be handled?

Waste containing 5-Methyl-2,4-bis[(trimethylsilyl)oxy]pyrimidine (CAS: 7288-28-0) should be managed according to the principles of waste minimization and proper disposal. Waste should be collected in appropriate, well-labeled containers, and stored in a secure area until disposal. Depending on local regulations, waste may need to undergo incineration or be treated by a professional hazardous waste disposal service. It is crucial to follow all environmental protection precautions to ensure that the waste is handled safely and efficiently, minimizing any environmental impact.