17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1)

Basic Information

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CAS Number

7280-37-7

Molecular Formula

C22H32N2O5S

Molecular Weight

436.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Physical State

No data available

Melting Point

No data available

Boiling Point

°Cat760mmHg

Solubility

DMSO: ≥24mg/mL

Vapor Pressure

No data available

Specific Rotation

D25 +87.8° (c = 1 in 0.4% NaOH)

SMILES

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CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.C1CNCCN1

InChI

InChI=1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1

InChIKey

HZEQBCVBILBTEP-ZFINNJDLSA-N

LogP

2.4726

Topological Polar Surface Area

104.72999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

650

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H350 May cause cancer
Carcinogenicity

Synonyms & References

English

Sulestrex piperazine
EINECS 230-696-3
OGEN 2.5
NSC 758912
Estropipate (USP:INN:BAN)
SR-01000000235-5
piperazine estrone sulphate
Ortho-Est, Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with Piperazine(1:1)
A837628
DTXCID303005
Pipestrone
ESTROPIPATE [MART.]
Estropipate (USP)
Sulestrex
Estropipate
Estrone sulfate piperazine salt
Estrone Hydrogen Sulfate compound with Piperazine(1:1)
BCP9000662
ESTROPIPATE [USP MONOGRAPH]
OGEN .625
HMS2232O19
OGEN 1.25
SCHEMBL21577
NSC-758912
Conjugated estrogens: piperazine estrone sulfate
ESTROPIPATE [VANDF]
Estropipate [USP:INN:BAN]
HMS3714I17
ESTROPIPATE (USP-RS)
SMR001233296
Harmogen

MDL Number

MFCD00867399

FAQ

What regulatory guidelines apply to 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7)?

Regulatory guidelines for 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7) include GHS classification, which categorizes it as a hazardous material based on its reactivity and potential health effects. REACH regulations require manufacturers and importers to register the chemical if the annual tonnage exceeds 1 ton. Additionally, FDA regulations may apply for its use in pharmaceutical applications, and EPA guidelines govern its disposal to protect the environment.

Are there alternatives to 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7) in synthesis?

There are alternative reagents and starting materials that can be used in its synthesis. Common alternatives include other piperazine derivatives and other oxoestra-1,3,5(10)-triene analogs. These alternatives can offer similar functionality while potentially offering better safety profiles or reactivity in specific processes.

What is the market or research trend for 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7)?

The market for 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7) is growing due to its applications in pharmaceuticals and research. Recent trends show an increase in academic and industrial research focusing on its potential in hormone-related therapies and its use as a synthetic intermediate. Price trends are stable, but may fluctuate based on supply and demand in the pharmaceutical industry.

How should waste containing 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7) be handled?

Waste containing 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1) (CAS: 7280-37-7) should be managed according to local environmental regulations. Collect waste liquids in appropriate containers and store in a secure area. For disposal, consult with a hazardous waste management company for professional incineration or chemical treatment. Ensure environmental protection precautions, including proper ventilation and personal protective equipment, are followed to prevent contamination and exposure.