alpha1-17-ACTH

Basic Information

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CAS Number

7266-47-9

Molecular Formula

C95H145N29O23S

Molecular Weight

2093.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.48±0.1 g/cm3 (20 ºC 760 Torr),

SMILES

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CC(C)C(C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CNC=N5)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CO)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(CO)N

InChI

InChI=1S/C95H145N29O23S/c1-53(2)78(91(144)109-49-75(128)111-62(22-9-12-35-96)81(134)113-63(23-10-13-36-97)82(135)117-68(93(146)147)26-16-39-106-95(102)103)123-90(143)74-27-17-40-124(74)92(145)67(24-11-14-37-98)112-76(129)48-108-80(133)71(44-56-46-107-61-21-8-7-20-59(56)61)120-83(136)64(25-15-38-105-94(100)101)114-86(139)70(42-54-18-5-4-6-19-54)119-88(141)72(45-57-47-104-52-110-57)121-84(137)65(32-33-77(130)131)115-85(138)66(34-41-148-3)116-89(142)73(51-126)122-87(140)69(118-79(132)60(99)50-125)43-55-28-30-58(127)31-29-55/h4-8,18-21,28-31,46-47,52-53,60,62-74,78,107,125-127H,9-17,22-27,32-45,48-51,96-99H2,1-3H3,(H,104,110)(H,108,133)(H,109,144)(H,111,128)(H,112,129)(H,113,134)(H,114,139)(H,115,138)(H,116,142)(H,117,135)(H,118,132)(H,119,141)(H,120,136)(H,121,137)(H,122,140)(H,123,143)(H,130,131)(H,146,147)(H4,100,101,105)(H4,102,103,106)

InChIKey

MXNMAFWEFLFAJN-UHFFFAOYSA-N

LogP

-7.023059999999926

Topological Polar Surface Area

864.45 Å²

Hydrogen Bond Donor/Acceptor

38 / 52

Complexity

4310

Synonyms & References

English

(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-6-Amino-1-[(2S)-2-[[(2S)-1-[[2-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[[(1S)-4-carbamimidamido-1-carboxybutyl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]
AS-83199
7266-47-9
alpha1-17-ACTH
a1-17-Corticotropin
Adrenocorticotropic Hormone Fragment 1-17 human
ACTH (1-17)
ACTH (1-17), human
ADRENOCORTICOTROPIC HORMONE FRAGMENT 1-17
Adrenocorticotropic Hormone Fragment 1-17 human, rat
alpha1-17-Corticotropin
H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-OH
Synchrodyn

MDL Number

MFCD00133033

FAQ

What regulatory guidelines apply to alpha1-17-ACTH (CAS: 7266-47-9)?

Alpha1-17-ACTH (CAS: 7266-47-9) is subject to various regulatory guidelines including the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and FDA/EPA requirements for pharmaceutical and environmental safety. Manufacturers and handlers must comply with these regulations for proper labeling, storage, and disposal to ensure safety and regulatory adherence.

Are there alternatives to alpha1-17-ACTH (CAS: 7266-47-9) in synthesis?

In the synthesis of alpha1-17-ACTH (CAS: 7266-47-9), alternative reagents and methods may include analogs such as alpha1-16-ACTH and other corticotropin fragments. Common alternatives include using isomers or different synthetic pathways to achieve similar biological activity, which can be more cost-effective or easier to synthesize depending on the specific application.

What is the market or research trend for alpha1-17-ACTH (CAS: 7266-47-9)?

The market for alpha1-17-ACTH (CAS: 7266-47-9) is driven by its use in research and development, particularly in endocrinology and immunology studies. Recent trends show increased interest in understanding its therapeutic potential for treating conditions like adrenal insufficiency. Research is also exploring its role in modulating the immune system and its potential as a drug candidate.

How should waste containing alpha1-17-ACTH (CAS: 7266-47-9) be handled?

Waste containing alpha1-17-ACTH (CAS: 7266-47-9) should be handled with care to prevent environmental contamination and ensure safety. Collect waste in appropriate containers, label them clearly, and dispose of them through a professional hazardous waste disposal service. Follow local and national regulations for waste management to ensure compliance and minimize environmental impact.