Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate

Basic Information

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CAS Number

72597-18-3

Molecular Formula

C13H17NO3

Molecular Weight

235.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

382°C at 760 mmHg

Density

1.135 g/mL at 25 °C

Refractive Index

n20/D 1.5396

SMILES

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C1CC(N(C1)C(=O)OCC2=CC=CC=C2)CO

InChI

InChI=1S/C13H17NO3/c15-9-12-7-4-8-14(12)13(16)17-10-11-5-2-1-3-6-11/h1-3,5-6,12,15H,4,7-10H2/t12-/m1/s1

InChIKey

BJTNHGVCFWDNDP-GFCCVEGCSA-N

LogP

1.7799

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

251

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

(R)-2-hydroxymethyl-1-pyrrolidine carboxylic acid phenylmethyl ester
N-Cbz-D-Prolinol
AKOS015836791
AC-23783
Benzyl (R)-2-hydroxymethylpyrrolidine-1-carboxylate
(R)-Benzyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate ee
(R)-BENZYL 2-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE
MFCD02683223
Cbz-D-prolinol
benzyl (R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
A837572
DTXSID20415632
Z-D-Prolinol, 97
(R)-2-Hydroxymethylpyrrolidine-1-carboxylic acid benzyl ester
benzyl (2R)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
XCA59718
ghl.PD_Mitscher_leg0.192
EN300-6299834
Z-D-Prolinol, 97%
AB22120
CS-W012891
(R)-BENZYL2-(HYDROXYMETHYL)PYRROLIDINE-1-CARBOXYLATE
Z-D-Prolinol
SCHEMBL5267939
DS-13331
(2R)-N-benzyloxycarbonyl-2-hydroxymethylpyrrolidine
72597-18-3
BJTNHGVCFWDNDP-GFCCVEGCSA-N
Cbz-D-Prolinol
(R)-Benzyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
(R)-N-Cbz-prolinol

MDL Number

MFCD02683223

Customs Code

2933990090

FAQ

What is Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3)?

Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) is an organic compound with a molecular structure that includes a benzyl group attached to a pyrrolidine ring with a hydroxymethyl substituent. It is a colorless or light yellow liquid with a distinctive odor. It is used in pharmaceuticals, research, and as a precursor in synthetic organic chemistry.

What are the main uses of Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3)?

Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also utilized in research for developing new chemical substances and in the chemical industry as a precursor for other organic compounds.

Is Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) safe?

Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) is considered safe when handled with appropriate precautions. It is important to follow safety guidelines, including the use of personal protective equipment (PPE) such as gloves and goggles, and to store it in a well-ventilated area. Avoid contact with eyes, skin, and inhalation of vapors. Proper disposal methods should be followed to prevent environmental contamination.

How should Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) be stored?

Benzyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate (CAS: 72597-18-3) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly closed container to prevent exposure to air and moisture. Store it at a temperature not exceeding 25°C and avoid freezing. It is important to store it in a well-ventilated area to minimize the risk of fire and explosion.