4-(4-Morpholinyl)-2-pyridinamine

Basic Information

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CAS Number

722549-98-6

Molecular Formula

C9H13N3O

Molecular Weight

179.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Flash Point

190.693℃

SMILES

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C1COCCN1C2=CC(=NC=C2)N

InChI

InChI=1S/C9H13N3O/c10-9-7-8(1-2-11-9)12-3-5-13-6-4-12/h1-2,7H,3-6H2,(H2,10,11)

InChIKey

KEQRMEXRBFYCCN-UHFFFAOYSA-N

LogP

0.5004000000000003

Topological Polar Surface Area

51.379999999999995 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

159

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A866291
SCHEMBL114416
KEQRMEXRBFYCCN-UHFFFAOYSA-N
2-Amino-4-(morpholin-4-yl)pyridine
SY008529
4-Morpholin-4-ylpyridin-2-amine
4-Morpholinopyridin-2-amine
AMY5647
722549-98-6
TS-02501
MFCD09991750
4-(Morpholin-4-yl)pyridin-2-amine
4-morpholin-4-yl-pyridin-2-ylamine
2-Amino-4-morpholinopyridine
XDB54998
DTXSID10620314
AKOS006280794
AC-31902
FT-0754161
2-AMINO-4-MORPHOLINOPYRIDINE
4-morpholin-4-yl-2-pyridylamine
4-(2-Aminopyridin-4-yl)morpholine
SBB051807
KM1464
TRA0040573

MDL Number

MFCD09991750

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6)?

4-(4-Morpholinyl)-2-pyridinamine is a white to off-white crystalline solid (CAS: 722549-98-6). Its molecular weight is approximately 254.36 g/mol. It is soluble in water and various organic solvents. Chemically, it is relatively stable but can undergo hydrolysis in acidic or basic conditions. It is mildly basic and can be used as a proton acceptor.

How is 4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6) typically synthesized?

4-(4-Morpholinyl)-2-pyridinamine can be synthesized via the reaction of 2-pyridinemethanamine with morpholine. Common methods include the multistep synthesis involving N-morpholinoacetylimidazole followed by reduction. This synthesis typically yields a product with a high degree of purity and selectivity. The reaction conditions are usually carried out under an atmosphere of nitrogen to prevent side reactions.

What industries use 4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6)?

4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6) is primarily used in the pharmaceutical industry for its pharmacological properties. It is also used in the polymer industry as a cross-linking agent. Additionally, it finds applications in sensor technology and as a precursor in the synthesis of other compounds. Its applications are expanding due to its unique chemical properties.

What precautions should be taken when handling 4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6)?

When handling 4-(4-Morpholinyl)-2-pyridinamine (CAS: 722549-98-6), it is important to use personal protective equipment (PPE) such as gloves, goggles, and lab coat to protect against skin and eye contact. This compound should be stored in a cool, dry place away from direct sunlight and heat sources. Proper ventilation is essential during handling and synthesis. In case of spills, clean up immediately using appropriate absorbent materials and dispose of waste according to local regulations. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.