1-(4-Chloro-2-fluorophenyl)methanamine

Basic Information

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CAS Number

72235-57-5

Molecular Formula

C7H7ClFN

Molecular Weight

159.59 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

SMILES

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C1=CC(=C(C=C1Cl)F)CN

InChI

InChI=1S/C7H7ClFN/c8-6-2-1-5(4-10)7(9)3-6/h1-3H,4,10H2

InChIKey

ODMMHGMIZYLHNN-UHFFFAOYSA-N

LogP

1.9378

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

110

Safety Information

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Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

AC-25945
AS-45904
SB76555
DTXSID60369286
J-514941
Benzenemethanamine, 4-chloro-2-fluoro-
TIMTEC-BB SBB003972
A19821
(4-chloro-2-fluorophenyl)methanamine
SY104508
4-Chloro-2-fluorobenzylamine, AldrichCPR
AKOS000169781
MFCD06212852
Benzenemethanamine,4-chloro-2-fluoro-
4-CHLORO-2-FLUOROBENZYL AMINE
4-Chloro-2-fluorobenzylamine
2-fluoro-4-chlorobenzylamine
CS-0094798
CK2426
72235-57-5
SCHEMBL992833
ODMMHGMIZYLHNN-UHFFFAOYSA-N
(4-Chloro-2-fluorophenyl)methanamine

MDL Number

MFCD06212852

Customs Code

2921499090

FAQ

What regulatory guidelines apply to 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5)?

1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) falls under the regulatory framework of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), requiring proper hazard communication. In Europe, it is also subject to the REACH regulation, which aims to ensure the safe use of chemicals. Additionally, the Food and Drug Administration (FDA) and Environmental Protection Agency (EPA) in the U.S. have specific requirements for handling and reporting this compound.

Are there alternatives to 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) in synthesis?

Several alternatives to 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) exist in synthesis, such as using 1-(3-Chloro-2-fluorophenyl)methanamine or 1-(4-Fluoro-2-methylphenyl)methanamine. These alternatives can offer similar functional groups for synthesis but with different substituents. Common reagents like 2-chloro-4-fluoroaniline can also be used as precursors.

What is the market or research trend for 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5)?

The market for 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) is driven by its use in pharmaceutical intermediates and material sciences. Research trends are focusing on its application in drug discovery and development, where it serves as a key building block. Recent studies are also exploring its potential in polymer synthesis and as an antibacterial agent.

How should waste containing 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) be handled?

Waste containing 1-(4-Chloro-2-fluorophenyl)methanamine (CAS: 72235-57-5) should be collected in appropriate containers and disposed of according to hazardous waste regulations. Incineration is a common method for disposal, but professional waste management services should be utilized. Environmental protection measures include proper ventilation and the use of protective gear to ensure safe handling and disposal. Compliance with local environmental laws and regulations is crucial.