1-(3,4-Difluorophenyl)methanamine

Basic Information

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CAS Number

72235-53-1

Molecular Formula

C7H7F2N

Molecular Weight

143.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

Boiling Point

179°C (rough estimate)

Density

1.21 g/mL at 25 °C

Refractive Index

n20/D 1.493(lit.)

SMILES

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C1=CC(=C(C=C1CN)F)F

InChI

InChI=1S/C7H7F2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H,4,10H2

InChIKey

PHLZUDXEBCQHKM-UHFFFAOYSA-N

LogP

1.4235

Topological Polar Surface Area

26.02 Å²

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

108

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Air Sensitive

Synonyms & References

English

(3,4-Difluorophenyl)methanamine;3,4-Difluorobenzenemethanamine
1-(3,4-DIFLUOROPHENYL)METHANAMINE
SB75403
MFCD00010145
PHLZUDXEBCQHKM-UHFFFAOYSA-
AKOS000130870
CS-0127972
NS00061401
EINECS 276-503-6
D3373
InChI=1/C7H7F2N/c8-6-2-1-5(4-10)3-7(6)9/h1-3H,4,10H2
PS-8994
(3,4-Difluorobenzyl)amine
AC-7423
A22200
3,4-difluorobenzyl amine
3,4-difluoro-benzylamine
SCHEMBL110823
[(3,4-difluorophenyl)methyl]amine
DTXSID00222548
Z239626576
72235-53-1
AM20041079
3,4-difluorobenzyl-amine
W-104493
FT-0614287
Benzenemethanamine, 3,4-difluoro-
3,4-Difluorobenzylamine, 98%
(3,4-Difluorophenyl)methanamine
CK2423
3,4-Difluorobenzylamine, tech

MDL Number

MFCD00010145

Customs Code

2921499090

FAQ

What regulatory guidelines apply to 1-(3,4-Difluorophenyl)methanamine (CAS: 72235-53-1)?

1-(3,4-Difluorophenyl)methanamine (CAS: 72235-53-1) is subject to regulatory guidelines including REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) in the EU, which requires detailed safety data sheets (SDS) and registration for manufacturers and importers. In the US, it falls under the jurisdiction of the EPA and FDA for specific applications. GHS (Globally Harmonized System of Classification and Labeling of Chemicals) categorizes this compound based on its health and environmental hazards.

Are there alternatives to 1-(3,4-Difluorophenyl)methanamine in synthesis?

There are several alternatives to 1-(3,4-Difluorophenyl)methanamine in synthesis, including analogs such as 1-(4-fluorophenyl)methanamine and 1-(3-chlorophenyl)methanamine. Additionally, common alternative reagents like methanol and other amine compounds can be used as substitutes depending on the specific reaction conditions and desired product properties.

What is the market or research trend for 1-(3,4-Difluorophenyl)methanamine?

The market trend for 1-(3,4-Difluorophenyl)methanamine (CAS: 72235-53-1) reflects growing interest in its use as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Research is focusing on its application in developing novel drug candidates and crop protection chemicals. Market trends indicate increasing demand driven by advancements in drug discovery and agricultural biotechnology.

How should waste containing 1-(3,4-Difluorophenyl)methanamine be handled?

Waste containing 1-(3,4-Difluorophenyl)methanamine (CAS: 72235-53-1) should be collected in appropriate containers and stored separately to prevent environmental contamination. The waste should be neutralized if necessary and disposed of according to local hazardous waste regulations. Incineration or professional waste disposal services are recommended to ensure safe and environmentally friendly disposal. Compliance with EPA and OSHA regulations is essential to protect workers and the environment.