2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline | CAS No. 721960-43-6
2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
Basic Information
CAS Number
721960-43-6
Molecular Formula
C12H17BClNO2
Molecular Weight
253.54 g/mol
AD
Basic Physical Properties
Synonyms & References
English
- SCHEMBL57994
- 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
- 4-amino-3-chlorophenylboronic acid pinacol ester
- EN300-7359497
- 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-aniline
- SY007769
- AS-31192
- MFCD09998359
- 721960-43-6
- 4-Amino-3-chlorophenylboronic acid pinacol ester, AldrichCPR
- (4-AMINO-3-CHLOROPHENYL)BORONIC ACID PINACOL ESTER
- AKOS015950532
- 2-chloro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylamine
- 4-AMINO-3-CHLOROPHENYLBORONIC ACID, PINACOL ESTER
- BCP16755
- 2-chloro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
- 4-Amino-3-chlorobenzeneboronic acid, pinacol ester
- 4-Amino-3-chlorophenylboronicAcidPinacolEster
- BEXOYZKPTUJSCZ-UHFFFAOYSA-N
- CS-0101292
- DTXSID70656997
- 4-Amino-3-chlorophenylboronic Acid Pinacol Ester
- Benzenamine, 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- PubChem18812
- ZXBA000508
- OR13797
- FCH2830279
- S
- 2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline
MDL Number
MFCD09998359
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 721960-43-6)?
2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is a solid with a crystalline form. It has a molecular weight of 354.12 g/mol and a melting point of 75-77°C. The compound is slightly soluble in water but soluble in organic solvents like ethanol and acetone. It is synthetically reactive, particularly in the presence of boron-containing reagents and can undergo substitution reactions under appropriate conditions.
How is 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 721960-43-6) typically synthesized?
2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is synthesized via a boronate ester formation reaction. The process involves the reaction of 2-chloroaniline with bis(pinacolato)diboron in the presence of a catalyst such as Pd(PPh3)2 or PdCl2(dppf) and a base like potassium acetate. The yield and selectivity of the product can be influenced by the choice of catalyst and reaction conditions.
What industries use 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 721960-43-6)?
2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline is used in the pharmaceutical industry for the synthesis of various bioactive compounds. It is also utilized in polymer synthesis, where it serves as a monomer or functional group. Additionally, it has applications in sensor technology and semiconductor manufacturing due to its unique chemical properties.
What precautions should be taken when handling 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS: 721960-43-6)?
When handling 2-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline, it is important to use appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed information on handling and disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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