5-Chloro-2-methylpyridine

Basic Information

View in Editor

CAS Number

72093-07-3

Molecular Formula

C6H6ClN

Molecular Weight

127.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

View in Editor

CC1=NC=C(C=C1)Cl

InChI

InChI=1S/C6H6ClN/c1-5-2-3-6(7)4-8-5/h2-4H,1H3

InChIKey

DEMKNLXJQNYAFY-UHFFFAOYSA-N

LogP

2.04342

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

74.9

Synonyms & References

English

2-METHYL-5-CHLOROPYRIDINE
AB17956
DEMKNLXJQNYAFY-UHFFFAOYSA-N
SY011807
A837421
CS-W005312
72093-07-3
MFCD04114188
5-Chloro-2-picoline
SCHEMBL111140
AMY6284
5-chloro-2-methylpyridine
EN300-90664
5-chloro-2-methyl-pyridine
DTXSID10376526
FT-0650004
PYRIDINE, 5-CHLORO-2-METHYL-
DS-12871
AKOS006228306
5-Chloro-2-methylpyridine
3-CHLORO-6-METHYLPYRIDINE
Pyridine,5-chloro-2-methyl-
PubChem6694
zlchem 1032
5-chloranyl-2-methyl-pyridine
ZLD0498
FCH832247
BBL101715
STL555512
OR345400
AB0053839

MDL Number

MFCD04114188

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 5-Chloro-2-methylpyridine (CAS: 72093-07-3)?

5-Chloro-2-methylpyridine is a crystalline solid with a molecular weight of approximately 136.57 g/mol. It has a solubility of about 1.3 g/L in water and is soluble in organic solvents like ethanol and acetone. Chemically, it is moderately reactive, displaying basic properties and can undergo substitution reactions. It is a key intermediate in the synthesis of various pharmaceuticals and pesticides.

How is 5-Chloro-2-methylpyridine (CAS: 72093-07-3) typically synthesized?

5-Chloro-2-methylpyridine is typically synthesized by alkylation of 2-chloropyridine with methyl chloride in the presence of a Lewis acid catalyst such as aluminum chloride. The reaction proceeds with good selectivity and yield, making it a common method for the preparation of this compound in industrial settings.

What industries use 5-Chloro-2-methylpyridine (CAS: 72093-07-3)?

5-Chloro-2-methylpyridine is primarily used in the pharmaceutical and pesticide industries as an intermediate. It plays a crucial role in the synthesis of various drugs and agrochemicals. Additionally, it is used in the production of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 5-Chloro-2-methylpyridine (CAS: 72093-07-3)?

When handling 5-Chloro-2-methylpyridine, it is essential to use appropriate personal protective equipment (PPE), including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for complete safety information and guidelines.