2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate

Basic Information

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CAS Number

719999-54-9

Molecular Formula

C10H20N2O2

Molecular Weight

200.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Colorless to Yellow Liquid

Boiling Point

303.9℃ at 760 mmHg

Density

0.997

SMILES

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CC(C)(C)OC(=O)NCC1CCCN1

InChI

InChI=1S/C10H20N2O2/c1-10(2,3)14-9(13)12-7-8-5-4-6-11-8/h8,11H,4-7H2,1-3H3,(H,12,13)/t8-/m1/s1

InChIKey

DPJPFGHHTJLWQQ-MRVPVSSYSA-N

LogP

1.2631

Topological Polar Surface Area

50.36 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

199

Safety Information

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GHS Hazard Pictograms

H410

Hazard Statement

H410 Very toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Synonyms & References

English

tert-Butyl {[(2R)-pyrrolidin-2-yl]methyl}carbamate
(R)-1-pyrrolidin-2-ylmethyl-carbamic acid tert-butyl ester
(r)-2-(boc-aminomethyl)-pyrrolidine
(r)-tert-butyl pyrrolidin-2-ylmethylcarbamate
Carbamic acid, [(2R)-2-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
AS-37088
AMY4383
(R)-1-pyrrolidin-2-ylmethylcarbamic acid tert-butyl ester
AKOS005258607
CS-W021147
Q-102893
(R)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate
719999-54-9
(2R)-2-(N-tert-butoxycarbonylaminomethyl)pyrrolidine
SCHEMBL79825
DPJPFGHHTJLWQQ-MRVPVSSYSA-N
MFCD03839886
(R)-2-tert-butoxycarbonylaminomethylpyrrolidine
tert-butyl N-{[(2R)-pyrrolidin-2-yl]methyl}carbamate
EN300-316922
(R)-2-N-Boc-Aminomethylpyrrolidine
tert-butyl N-[[(2R)-pyrrolidin-2-yl]methyl]carbamate
Carbamic acid,[(2R)-2-pyrrolidinylmethyl]-,1,1-dimethylethyl ester(9ci)
(R)-2-(Boc-aminomethyl)pyrrolidine
((2r)-2-pyrrolidinylmethyl)carbamic acid tert-butyl ester
(R)-2-N-Boc-aminomethylpyrrolidine, AldrichCPR
DTXSID90628732
(r)-pyrrolidin-2-ylmethyl-carbamic acid tert-butyl ester
(R )-pyrrolidin-2-ylmethyl-carbamic acid tert-butyl ester
(R)-tert-butyl pyrrolidin-2-ylmethylcarbamate
Carbamic acid,N-[(2R)-2-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester

MDL Number

MFCD03839886

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9)?

2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9) is a colorless liquid with a molecular weight of approximately 252.33 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and acetone. The compound is moderately reactive, particularly with basic compounds. It is stable under normal conditions but should be stored away from direct sunlight and strong oxidizers to prevent degradation.

How is 2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9) typically synthesized?

2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9) is typically synthesized through the reaction of 2-methyl-2-propanol with (2R)-2-pyrrolidinylmethylamine under milder conditions, often using a base like sodium hydride as a catalyst. The reaction yields a high purity product with good selectivity and high yield, making it a suitable method for industrial production.

What industries use 2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9)?

2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of complex organic compounds. It also finds applications in the production of certain polymers and as a reagent in analytical chemistry, particularly in sensing and as a molecular probe for various analytical techniques.

What precautions should be taken when handling 2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9)?

When handling 2-Methyl-2-propanyl [(2R)-2-pyrrolidinylmethyl]carbamate (CAS: 719999-54-9), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or under a fume hood to avoid inhalation of vapors. In case of a spill, it should be immediately cleaned up using appropriate absorbents. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.