O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine

Basic Information

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CAS Number

71989-40-7

Molecular Formula

C31H27NO5

Molecular Weight

493.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

157-161 °C

Density

1.2710

SMILES

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C1=CC=C(C=C1)COC2=CC=C(C=C2)CC(C(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

InChI

InChI=1S/C31H27NO5/c33-30(34)29(18-21-14-16-23(17-15-21)36-19-22-8-2-1-3-9-22)32-31(35)37-20-28-26-12-6-4-10-24(26)25-11-5-7-13-27(25)28/h1-17,28-29H,18-20H2,(H,32,35)(H,33,34)/t29-/m0/s1

InChIKey

REHSJSKPWIOKIJ-LJAQVGFWSA-N

LogP

5.800000000000005

Topological Polar Surface Area

84.86 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

722

Synonyms & References

English

(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phenylmethoxyphenyl)propanoic acid
3-(4-benzyloxyphenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid
N-Fmoc-4-benzyloxyl-L-phenylalanine
Fmoc-Tyr(Bzl)-OH, >=98.0% (HPLC)
O-Benzyl-N-{[(9H-fluoren-9-yl)methoxy]carbonyl}-L-tyrosine
Fmoc-O-benzyl-D-Tyr
71989-40-7
Fmoc-Tyr(Bzl)
fmoc-O-benzyltyrosine
Fmoc-Tyr(Bzl)-OH
CS-M3676
DS-14680
MFCD00065682
AKOS015906439
HY-79132
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(benzyloxy)phenyl)propanoic acid
(s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-3-(4-(benzyloxy)phenyl)propanoic acid
(2S)-3-[4-(benzyloxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
SCHEMBL2305316
L-Tyrosine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-
Fmoc-Tyr(Bzl)-OH Fmoc-O-benzyl-L-tyrosine
EN300-651077
AKOS015924186
M03430
DTXSID30560162
N-Fmoc-O-benzyl-L-tyrosine
N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-benzyl-L-tyrosine
A837393
fmoc-O-benzyl-L-tyrosine
Fmoc-L-Tyr(Bzl)-OH
9-fluorenylmethoxycarbonyl-3-(4-benzyloxyphenyl)-L-alanine

MDL Number

MFCD00065682

FAQ

What is O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7)?

O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7) is an amino acid derivative used primarily in medicinal chemistry and pharmaceutical research. It is a protected tyrosine derivative featuring a fluorenylmethoxycarbonyl (Fmoc) group attached to the alpha-amino group and a benzyloxy group at the para position of the benzyl ring.

What are the main uses of O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7)?

O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine is extensively used in the synthesis of various peptides and proteins due to its protective nature. It serves as a key intermediate in the solid-phase synthesis of peptides and plays a crucial role in research and development of pharmaceuticals.

Is O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7) safe?

O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7) is generally considered safe when handled with appropriate precautions. However, it is mildly toxic if ingested and should be stored in a cool, dry place away from heat and direct sunlight. Protective gloves and goggles should be worn during handling and disposal should be in accordance with regulatory guidelines.

How should O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7) be stored?

O-Benzyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine (CAS: 71989-40-7) should be stored in a tightly sealed container at a temperature range of 4-8°C (39-46°F). It is essential to keep the compound away from heat, moisture, and direct sunlight to maintain its stability. Ensure the storage area is well-ventilated and the container is secure to prevent spills and leaks.