N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine | CAS No. 71989-38-3

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine

Basic Information

CAS Number

71989-38-3

Molecular Formula

C28H29NO5

Molecular Weight

459.54 g/mol

AD

Basic Physical Properties

Melting Point

150.0 to 154.0 deg-C

Boiling Point

658.2°C at 760 mmHg

Density

1.2180

Flash Point

351.9±31.5 °C

Refractive Index

-30 ° (C=1, DMF)

Specific Rotation

-28 º (c=1, DMF)

CC(C)(C)OC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)/t25-/m0/s1

InChIKey

JAUKCFULLJFBFN-VWLOTQADSA-N

LogP

5.398300000000004

Topological Polar Surface Area

84.86 Ų

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

673

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • AS-14179
  • EN300-96349
  • (2S)-3-(4-(tert-butoxy)phenyl)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)propanoic acid
  • F0506
  • (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
  • Fmoc-Tyr(tBu)-OH, >=98.0% (HPLC)
  • Fmoc-Tyr(t-Bu)-OH
  • Fmoc-Tyr(tBu)
  • Nalpha-Fmoc-O-tert-butyl-L-tyrosine
  • Fmoc-O-tert-butyl-L-tyrosine
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine
  • Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-tyrosine
  • N-Fmoc-O-tert-butyl-tyrosine
  • M03428
  • O-tert-Butyl-Nalpha-Fmoc-L-tyrosine
  • 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-TYROSINE
  • NS00063239
  • (s)-3-(4-tert-butoxy-phenyl)-2-(9h-fluoren-9-ylmethoxycarbonylamino)-propionic acid
  • Fmoc-Tyr(tBu)-OH
  • N-Fmoc-O-tert-butyl-L-tyrosine
  • Fmoc-O-tert.butyl-L-tyrosine
  • (2S)-3-[4-(tert-butoxy)phenyl]-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • (4-METHYL-2,5-DIOXO-4-PHENYLIMIDAZOLIDIN-1-YL)ACETICACID
  • FmocTyr(tBu)OH
  • Fmoc-L-Tyr(tBu)-OH
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosine
  • Q-101757
  • (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-tert-butoxyphenyl)propanoic acid
  • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoic acid
  • CS-W008016
  • MFCD00037129

MDL Number

MFCD00037129

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 71989-38-3)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine is a derivative of the amino acid L-tyrosine. It contains a fluorenylmethoxy group and a tert-butyl group, making it a protected amino acid commonly used in organic synthesis. Its chemical formula is C23H29NO4, and it is typically a white to pale yellow solid with good solubility in organic solvents.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 71989-38-3)?

This compound is widely used in pharmaceutical research as a building block for drug development. It also finds applications in the synthesis of peptides, proteins, and other bioactive molecules. In industrial settings, it may be used as a reagent in organic chemistry processes. Its use in food is limited, but it is often employed in laboratory research for functional group studies and chemical modifications.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 71989-38-3) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine is generally considered safe when handled properly. However, as a chemical reagent, it should be treated with caution. It is advisable to use gloves, goggles, and a fume hood during handling. Safety data sheets (SDS) should be consulted for detailed information on toxicity and exposure limits.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(2-methyl-2-propanyl)-L-tyrosine (CAS: 71989-38-3) be stored?

This compound should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is best kept in a sealed container to prevent moisture absorption and degradation. Avoid exposure to light and air to maintain its stability. Proper storage is essential to preserve its chemical integrity and ensure safe handling.

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