N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine

Basic Information

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CAS Number

71989-26-9

Molecular Formula

C26H32N2O6

Molecular Weight

468.55 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

124°C

Boiling Point

685.7°C at 760 mmHg

Density

1.2301 (rough estimate)

Water Solubility

Slightly soluble in water.

Flash Point

368.5℃

Refractive Index

-12 ° (C=1, DMF)

Specific Rotation

-12 º (c=2,DMF 24 ºC)

SMILES

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CC(C)(C)OC(=O)NCCCCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1

InChIKey

UMRUUWFGLGNQLI-QFIPXVFZSA-N

LogP

4.673300000000004

Topological Polar Surface Area

113.96000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

684

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Stable. Incompatible with strong oxidizing agents.

Sensitiveness

thermally sensitive

Synonyms & References

English

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE
(2S)-6-{[(tert-butoxy)carbonyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
N-alpha-Fmoc-N-epsilon-boc-L-lysine
J-300176
N-alpha-Fluorenylmethoxycarbonyl-N-epsilon-tert-butoxycarbonyl-L-lysine
N-alpha-FMOC-N-epsilon-tert-boc-L-lysine
NS00064248
(s)-2-(((9h-fluoren-9-yl)methoxy)carbonylamino)-6-(tert-butoxycarbonylamino)hexanoic acid
Nepsilon-Boc-Nalpha-Fmoc-L-lysine
SCHEMBL1738182
AMY22567
N2-Fmoc-N6-BOC-L-lysine
N2-(((9H-fluoren-9-yl)methoxy)carbonyl)-N6-(tert-butoxycarbonyl)-L-lysine
(2S)-6-(tert-butoxycarbonylamino)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
HY-79128
CS-W019816
AC-27601
Fmoc-Lys(Boc)-OH, >=98.0% (HPLC)
Lysine derivative 3
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
B3072
L-Lysine, N(6)-[(1,1-dimethylethoxy)carbonyl]-N(2)-[(9H-fluoren-9-ylmethoxy)carbonyl]-
AKOS015892735
N-alpha-FMOC-Nepsilon-BOC-L-Lysine
A837386
CHEMBL178424
N6-Boc-N2-Fmoc-L-lysine
Nepsilon-(tert-Butoxycarbonyl)-Nalpha-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine
AS-14176
N-alpha-(Fmoc)-N-epsilon-(t-boc)-L-Lysine-OH
Fmoc-L-Lys (Boc)-OH

MDL Number

MFCD00037138

Customs Code

2924299090

FAQ

What is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9) is a synthetic compound used in chemical research. It is a derivative of L-lysine, featuring protected groups on the amino acids, making it useful in peptide synthesis and drug development. The compound is typically solid at room temperature and has a high molecular weight.

What are the main uses of N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9)?

This compound is primarily used in pharmaceutical and biochemical research for its role in peptide synthesis. It serves as a building block for complex molecules, including potential drug candidates. Its protected amino groups allow for controlled chemical reactions, enhancing its utility in synthetic organic chemistry and medicinal chemistry applications.

Is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9) safe?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9) is generally considered safe when handled properly. However, as with many chemical compounds, it should be used with appropriate safety measures, including wearing personal protective equipment (PPE) and working in a well-ventilated area. It is not classified as highly toxic, but its safety profile should be evaluated based on specific handling conditions and regulatory guidelines.

How should N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9) be stored?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N~6~-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-lysine (CAS: 71989-26-9) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is best kept in a sealed container to prevent moisture exposure and contamination. Avoid exposure to air and light to maintain its stability and prevent degradation.