N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine

Basic Information

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CAS Number

71989-23-6

Molecular Formula

C21H23NO4

Molecular Weight

353.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

146.0 to 149.0 deg-C

Boiling Point

486.83°C (rough estimate)

Density

1.208

Flash Point

292.4℃

Solubility

Soluble in methanol (very faint turbidity).

Refractive Index

1.582

Specific Rotation

-12 º (c=1,DMF)

SMILES

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CCC(C)C(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

InChI

InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13?,19-/m0/s1

InChIKey

QXVFEIPAZSXRGM-YFKXAPIDSA-N

LogP

4.024400000000003

Topological Polar Surface Area

75.63 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

486

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(2S,3S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylpentanoic acid
Fmoc-Ile-OH, >=98.0% (T)
Fmoc-Ile-OH
EN300-74033
Q-102750
NCGC00142579-01
M03362
A837384
(((9H-fluoren-9-yl)methoxy)carbonyl)-L-isoleucine
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucine #
DTXSID801315561
N-(Fluoren-9-ylmethoxycarbonyl)-L-isoleucine
(2S,3S)-2-[(fluoren-9-ylmethoxy)carbonylamino]-3-methylpentanoic acid
F0294
Fmoc-L-Ile-OH
N-Fmoc-Ile-OH ( N-Fmoc-L-isoleucine)
9-FLUORENYLMETHOXYCARBONYL-L-ISOLEUCINE
N-Fmoc-L-isoleucine
HY-19821
L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
MFCD00037125
Fmoc-Ile-OH Fmoc-(2S,3S)-2-amino-3-methylpentanoic acid
AS-56836
FMOC-ILE
AKOS015924098
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine
BRD-K24518485-001-01-0
N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine; 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoic acid; Fmoc-Ile-OH
71989-23-6
(2S,3S)-2-((((9H-FLUOREN-9-YL)METHOXY)CARBONYL)AMINO)-3-METHYLPENTANOIC ACID
CS-W020667

MDL Number

MFCD00037125

Customs Code

2924299090

FAQ

What is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) is an organic compound that contains an L-isoleucine residue linked to a fluorene-9-ylmethoxy carbonyl group. It is commonly used as a building block in the synthesis of pharmaceuticals and bioactive molecules. The compound is typically a white to off-white solid with a molecular formula of C22H22N2O4 and a molecular weight of approximately 386.42 g/mol.

What are the main uses of N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6)?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) is primarily used in pharmaceutical research for the development of drugs targeting metabolic disorders and neurological conditions. It also finds applications in organic synthesis as a protected amino acid derivative, and in biochemistry for studying protein structures and enzymatic reactions.

Is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) safe?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) is generally considered safe when handled properly. However, as with many chemical compounds, it should be used with appropriate personal protective equipment (PPE) such as gloves and goggles. Safety data sheets (SDS) recommend avoiding inhalation and skin contact, and ensuring proper ventilation in the work area.

How should N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) be stored?

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine (CAS: 71989-23-6) should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is sensitive to moisture and light, so it is recommended to keep it in a sealed container with a desiccant. Avoid exposure to air and store away from incompatible substances to maintain stability and purity.