Artemether | CAS No. 71963-77-4

Artemether

Basic Information

CAS Number

71963-77-4

Molecular Formula

C16H26O5

Molecular Weight

298.38 g/mol

AD

Basic Physical Properties

Physical State

Powder

Melting Point

86.0 to 90.0 deg-C

Boiling Point

359.79°C (rough estimate)

Density

1.0733 (rough estimate)

Flash Point

141 °C

Solubility

DMSO: ≥20mg/mL

Refractive Index

1.6200 (estimate)

Vapor Pressure

4X10-5 mm Hg at 25 °C (est)

Specific Rotation

+166° - +173° (c=1,EtOH)

CO[C@H]1O[C@@H]2O[C@@]3(C)CC[C@H]4[C@H](C)CC[C@@H]([C@H]1C)[C@@]24OO3

InChI

InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1

InChIKey

SXYIRMFQILZOAM-HVNFFKDJSA-N

LogP

2.8408000000000015

Topological Polar Surface Area

46.150000000000006 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

429

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Toxicity

LD50 i.m. in mice: 263 mg/kg (China Cooperative Research Group on Qinghaosu)

Synonyms & References

English

  • Artemether
  • 3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin,decahydro-10-methoxy-3,6,9-trim
  • 5a-beta,6-beta,8a-beta,9-alpha,12-beta,12ar)-(3-alph(+)-ethyl
  • artemisininelactolmethylether
  • cgp56696
  • dihydroartemisininmethylether
  • dihydroquinghaosumethylether
  • methyl-dihydroartemisinine
  • [3r-(3r,5as,6s,8as,9r,10r,12s,12ar**)]-decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12h-pyrano[4,3-j]-1,2-benzodioxepin
  • AMMoniuM hexafluorophosphate
  • ArteMos
  • ArtenaM
  • Artesaph
  • Artesian
  • Dihydroqinghaosu methyl ether
  • Falcidol
  • Gvither
  • Larither
  • MalarteM
  • SM224
  • SM-224
  • Dihydroartemisinin methyl ether
  • DSSTox_RID_79521
  • DSSTox_CID_20651
  • DSSTox_GSID_40651
  • Tox21_112217
  • (4S,5R,8S,9R,10S,12R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]h
  • [3R-(3R,5aS,6S,8aS,9R,10R,12S,12aR**)]-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
  • (3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene

MDL Number

MFCD00866205

Customs Code

2932999099

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