Amisulpride | CAS No. 71675-85-9

Amisulpride

Basic Information

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CAS Number

71675-85-9

Molecular Formula

C17H27N3O4S

Molecular Weight

369.49 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Powder

Melting Point

125.0 to 129.0 deg-C

Boiling Point

558.9°C at 760 mmHg

Density

1.20 g/cm3

Flash Point

291.8 °C

Solubility

DMSO: ≥5 mg/mL

Refractive Index

1.545

SMILES

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CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC

InChI

InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)

InChIKey

NTJOBXMMWNYJFB-UHFFFAOYSA-N

LogP

1.2851000000000006

Topological Polar Surface Area

101.72999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

549

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Sensitiveness

Sensitive to heat, humidity, and light

Toxicity

LD50 in male mice (mg/kg): 56-60 i.v.; 175-180 i.p.; 224-250 s.c.; 1024-1054 orally (Thominet)

Synonyms & References

English

MLS006011769
BRD-A60197193-001-05-4
Tox21_113392_1
Socian
NCGC00092310-04
AMISULPRIDE [WHO-DD]
HMS3268L09
4-Amino-N-[(1-ethyl-2-pyrrolidinyl) methyl]-5-(ethylsulfonyl)-2-benzamide
Amisulpride [INN:BAN]
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
CCG-100860
Aminosultopride
AB00639933_10
Amisulpride for system suitability, European Pharmacopoeia (EP) Reference Standard
Amisulpridum [INN-Latin]
HMS3657E11
Amisulpiride
Amisulpride (INN)
W-104511
HMS3884A09
HMS3369K09
Amisulprida [INN-Spanish]
GTPL963
S1280
Tox21_501133
Amisulpride; 4-Amino-N-[[(2RS)-1-ethylpyrrolidin-2-yl]methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
MLS000759450
Amisulprida
Deniban
D07310
EN300-18166870

MDL Number

MFCD00866691

Customs Code

2933990090

FAQ

What is Amisulpride (CAS: 71675-85-9)?

Amisulpride (CAS: 71675-85-9) is an antipsychotic medication with the chemical formula C15H19N5S. It is a white crystalline powder, soluble in water and alcohol, and functions as a dopamine D2 receptor antagonist. Commonly used for treating schizophrenia and other psychiatric disorders, it is known for its selective action on dopamine receptors, minimizing extrapyramidal side effects.

What are the main uses of Amisulpride (CAS: 71675-85-9)?

Amisulpride (CAS: 71675-85-9) is primarily used as an atypical antipsychotic to manage schizophrenia, bipolar disorder, and depressive symptoms. Its therapeutic applications include alleviating hallucinations, delusions, and mood swings. It is also utilized in research for studying dopamine receptor modulation and its role in neurological conditions.

Is Amisulpride (CAS: 71675-85-9) safe?

Amisulpride (CAS: 71675-85-9) is generally safe when used as prescribed, but its safety profile depends on proper handling and medical supervision. While it has a favorable side effect profile compared to older antipsychotics, overdose or misuse can lead to toxicity. Always follow regulatory guidelines and consult healthcare professionals for safe use.

How should Amisulpride (CAS: 71675-85-9) be stored?

Amisulpride (CAS: 71675-85-9) should be stored in a cool, dry place (ideally 20-25°C), away from light and moisture. Keep in a sealed, airtight container to maintain stability and prevent degradation. Ensure storage conditions comply with safety standards to preserve efficacy and avoid chemical interactions.