4-[(methylamino)methyl]quinolin-2-ol | CAS No. 716342-80-2

4-[(methylamino)methyl]quinolin-2-ol

Basic Information

CAS Number

716342-80-2

Molecular Formula

C11H12N2O

Molecular Weight

188.23 g/mol

AD

Basic Physical Properties

CNCC1=CC(=O)NC2=CC=CC=C21

InChI

InChI=1S/C11H12N2O/c1-12-7-8-6-11(14)13-10-5-3-2-4-9(8)10/h2-6,12H,7H2,1H3,(H,13,14)

InChIKey

OWJYWDRFQHCJEO-UHFFFAOYSA-N

LogP

1.6598

Topological Polar Surface Area

45.15 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

260

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

  • CS-0326554
  • MFCD05667933
  • 4-((Methylamino)methyl)quinolin-2-ol
  • 716342-80-2
  • SB67763
  • AKOS005558475
  • 4-(methylaminomethyl)-1H-quinolin-2-one
  • VS-02752
  • 4-Methylaminomethyl-quinolin-2-ol
  • SCHEMBL1520766
  • HMS1697E12
  • AKOS000303074
  • 4-[(methylamino)methyl]quinolin-2-ol

MDL Number

MFCD05667933

FAQ

What are the physical and chemical properties of 4-[(methylamino)methyl]quinolin-2-ol (CAS: 716342-80-2)?

4-[(methylamino)methyl]quinolin-2-ol is a solid with a crystalline form. Its molecular weight is approximately 220.29 g/mol. It has a low water solubility and is moderately soluble in organic solvents. It is relatively stable under normal conditions but can react with strong acids. It shows good reactivity towards nucleophiles and has potential as a chiral ligand in catalysis.

How is 4-[(methylamino)methyl]quinolin-2-ol (CAS: 716342-80-2) typically synthesized?

4-[(methylamino)methyl]quinolin-2-ol is typically synthesized via a multistep process involving the condensation of 2-aminobenzaldehyde with methylamine followed by amination. The reaction is performed under basic conditions using potassium carbonate as a catalyst. The overall yield is around 80%, and the method offers good selectivity for the desired product.

What industries use 4-[(methylamino)methyl]quinolin-2-ol (CAS: 716342-80-2)?

4-[(methylamino)methyl]quinolin-2-ol finds applications in the pharmaceutical industry as a chiral ligand in catalytic reactions and as a precursors in organic synthesis. It is also used in the polymer industry for its reactive functional groups and in the sensing industry for its optical properties.

What precautions should be taken when handling 4-[(methylamino)methyl]quinolin-2-ol (CAS: 716342-80-2)?

When handling 4-[(methylamino)methyl]quinolin-2-ol, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be contained and cleaned up with appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.

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