2-Phenyl-1H-benzimidazole

Basic Information

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CAS Number

716-79-0

Molecular Formula

C13H10N2

Molecular Weight

194.24 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

293-296 °C

Boiling Point

320.68°C (rough estimate)

Density

1.1579 (rough estimate)

Water Solubility

Slightly soluble in water.

Flash Point

210℃

Refractive Index

1.5014 (estimate)

SMILES

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C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2

InChI

InChI=1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15)

InChIKey

DWYHDSLIWMUSOO-UHFFFAOYSA-N

LogP

3.2299000000000015

pKa

5.23(at 25℃)

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

211

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BDBM3789
Gainex
AB00876270-08
HMS3372F02
g 570
Tox21_303711
FT-0613322
NSC-251956
AF-407/01228019
CB9ZJ140SB
HMS2235H23
Q27275387
NSC 251956
EN300-16230
NS00005205
2-phenyl-1H-benzo[d]imidazole
1H-Benzimidazole, 2-phenyl-
Phenizidole
CHEMBL153535
2-Phenyl-1H-benzimidazole
NCGC00357026-01
CAS-716-79-0
SMR000526282
NSC251956
A15771
cid_12855
HMS1728H19
Z50129842
MLS000701325
BENZIMIDAZOLE, 2-PHENYL-
Phenzidol

MDL Number

MFCD00005592

FAQ

What is 2-Phenyl-1H-benzimidazole (CAS: 716-79-0)?

2-Phenyl-1H-benzimidazole is a heterocyclic organic compound with the molecular formula C14H10N2. It features a benzimidazole ring system substituted with a phenyl group, making it a key intermediate in pharmaceutical and industrial applications. This compound is typically a solid at room temperature, exhibits moderate solubility in organic solvents, and is valued for its stability and functional versatility in chemical synthesis.

What are the main uses of 2-Phenyl-1H-benzimidazole (CAS: 716-79-0)?

2-Phenyl-1H-benzimidazole is widely used in pharmaceuticals as a precursor for antifungal and antiparasitic drugs. It also serves in industrial applications, including UV stabilizers for plastics and dyes. In research, it is employed for developing new materials and as a building block for bioactive compounds. Its unique chemical structure makes it relevant for applications requiring functional group modification or molecular scaffolding.

Is 2-Phenyl-1H-benzimidazole (CAS: 716-79-0) safe?

2-Phenyl-1H-benzimidazole is generally considered safe when handled properly, but it may cause mild skin or eye irritation. Safety data sheets (SDS) recommend using personal protective equipment (PPE) like gloves and goggles during handling. It is classified as low toxicity in controlled environments, with adherence to OSHA and EPA guidelines ensuring safe use in laboratories and industrial settings.

How should 2-Phenyl-1H-benzimidazole (CAS: 716-79-0) be stored?

2-Phenyl-1H-benzimidazole should be stored in a cool, dry place, away from light and moisture. It is best kept in a sealed, airtight container to maintain stability. Storage conditions should avoid exposure to humidity and high temperatures, with some formulations requiring nitrogen atmosphere to prevent degradation. Proper storage ensures its chemical integrity and prolongs shelf life.