5,6,7,8-Tetrahydro-5-quinolinamine

Basic Information

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CAS Number

71569-15-8

Molecular Formula

C9H12N2

Molecular Weight

148.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

259.1 °C at 760 mmHg

Density

1.081

Flash Point

134.3 °C

Refractive Index

1.565

SMILES

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C1CC(C2=C(C1)N=CC=C2)N

InChI

InChI=1S/C9H12N2/c10-8-4-1-5-9-7(8)3-2-6-11-9/h2-3,6,8H,1,4-5,10H2

InChIKey

ZMAFTVCNAYZLGF-UHFFFAOYSA-N

LogP

1.4177000000000002

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

136

Synonyms & References

English

FT-0773405
CS-W022272
71569-15-8
5,6,7,8-tetrahydroquinolin-5-ylamine
ZMAFTVCNAYZLGF-UHFFFAOYSA-N
SCHEMBL1218171
PB24835
AKOS006240497
5,6,7,8-TETRAHYDRO-QUINOLIN-5-YLAMINE
5-Quinolinamine, 5,6,7,8-tetrahydro-
EN300-81580
AMY33882
DS-12769
CHEMBL1197410
SY111274
DTXSID50992128
FT-0705539
FT-0771320
5,6,7,8-tetrahydroquinolin-5-amine
MFCD04038438
5-Amino-5,6,7,8-tetrahydroquinoline
5,6,7,8-Tetrahydroquinolin-5-amine
5,6,7,8-Tetrahydro-quinolin-5-ylamine
5,6,7,8-tetrahydro-5-quinolinamine(SALTDATA: 2HCl)
5-Quinolinamine,5,6,7,8-tetrahydro
FCH919983
5780AH
AX8029477
A40050
569A158

MDL Number

MFCD04038438

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 5,6,7,8-Tetrahydro-5-quinolinamine (CAS: 71569-15-8)?

5,6,7,8-Tetrahydro-5-quinolinamine is a white crystalline solid with a molecular weight of approximately 173.22 g/mol. It is slightly water-soluble and has a basic nature. Chemically, it is highly reactive towards acids and can undergo nucleophilic substitution reactions. It is also susceptible to hydrolysis under basic conditions.

How is 5,6,7,8-Tetrahydro-5-quinolinamine (CAS: 71569-15-8) typically synthesized?

5,6,7,8-Tetrahydro-5-quinolinamine is typically synthesized through a multi-step process involving the reduction of quinoline derivatives and subsequent amine formation. Commonly, this involves the reduction of 5-quinolone to the corresponding amine using a suitable reducing agent like sodium borohydride or lithium aluminum hydride, followed by hydrogenation to obtain the tetrahydro derivative.

What industries use 5,6,7,8-Tetrahydro-5-quinolinamine (CAS: 71569-15-8)?

5,6,7,8-Tetrahydro-5-quinolinamine is used in the pharmaceutical industry for the synthesis of certain drug molecules due to its pharmacological properties. It is also applied in the polymer industry for the modification of polymers and in the development of sensors and semiconductors due to its electronic properties.

What precautions should be taken when handling 5,6,7,8-Tetrahydro-5-quinolinamine (CAS: 71569-15-8)?

When handling 5,6,7,8-Tetrahydro-5-quinolinamine, wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Always work in a well-ventilated area or fume hood. Store the compound in a cool, dry place away from flammable materials. In the event of a spill, immediately clean up using a suitable absorbent and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information on handling and emergency procedures.