5,6-Difluoro-1,3-dihydro-2H-indol-2-one

Basic Information

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CAS Number

71294-07-0

Molecular Formula

C8H5F2NO

Molecular Weight

169.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

285.3°C at 760 mmHg

Density

1.187

Flash Point

226.9 oC at 760 mmHg

Refractive Index

1.355

SMILES

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C1C2=CC(=C(C=C2NC1=O)F)F

InChI

InChI=1S/C8H5F2NO/c9-5-1-4-2-8(12)11-7(4)3-6(5)10/h1,3H,2H2,(H,11,12)

InChIKey

MSOLDJZABLHVER-UHFFFAOYSA-N

LogP

1.4594

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

209

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

W16701
MC10114
5 pound not6-Difluorooxindole
5,6-difluoro-1,3-dihydro-indol-2-one
MFCD01075216
5,6-difluoroxindole
71294-07-0
5, 6-difluorooxindole
DTXSID70503417
5,6-Difluoro-1,3-dihydro-2H-indol-2-one
CS-W022276
A9348
5,6-difluoro-1,3-dihydroindol-2-one
FT-0601326
2H-Indol-2-one, 5,6-difluoro-1,3-dihydro-
SY008528
SCHEMBL548762
5,6-Difluoro-2-oxindole
AC-22691
AKOS005215809
SB64225
AMY3654
5,6-Difluorooxindole
5,6-difluoro-2,3-dihydro-1H-indol-2-one
5,6-difluoroindolin-2-one;5,6-Difluoro-2-oxindole
5,6-Difluoro-2-oxoindole
J-516525
DS-12867
5,6-difluoroindolin-2-one
MSOLDJZABLHVER-UHFFFAOYSA-N
5,6-difluoro-oxindole

MDL Number

MFCD01075216

FAQ

What regulatory guidelines apply to 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0)?

5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) falls under various regulatory guidelines, including GHS (Global Harmonized System of Classification and Labeling of Chemicals), which classifies it based on its physical and health hazards. Additionally, it is subject to REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulations in the EU. In the US, it must comply with FDA and EPA requirements for chemical substances and pesticides.

Are there alternatives to 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) in synthesis?

Yes, there are several alternatives to 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) in synthesis, including 5-fluoro-1,3-dihydro-2H-indol-2-one and 6-fluoro-1,3-dihydro-2H-indol-2-one. Other substitute reagents like 4-fluorobenzaldehyde and 2-fluoroacetyl chloride can also be used as precursors for similar compounds.

What is the market or research trend for 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0)?

The market for 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) shows increasing interest in its use as a pharmaceutical intermediate and in the development of selective inhibitors for various enzymes. Research trends indicate a focus on its application in drug discovery and development, particularly in oncology and neurology. The compound's demand is expected to grow due to its potential in these fields.

How should waste containing 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) be handled?

Waste containing 5,6-Difluoro-1,3-dihydro-2H-indol-2-one (CAS: 71294-07-0) should be handled according to local and international regulations. It is recommended to collect waste in appropriate containers and dispose of it through professional waste disposal services. Incineration is a viable method, provided it is done in an enclosed system to minimize emissions. Environmental protection measures include ensuring no spillage and proper ventilation during handling and disposal to protect both human health and the environment.