5-Chloro-2-hydroxybenzamide

Basic Information

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CAS Number

7120-43-6

Molecular Formula

C7H6ClNO2

Molecular Weight

171.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

233.0 to 237.0 deg-C

Boiling Point

301.6 °C at 760 mmHg

Density

1.447

Flash Point

136.2 °C

Refractive Index

1.626

SMILES

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C1=CC(=C(C=C1Cl)C(=O)N)O

InChI

InChI=1S/C7H6ClNO2/c8-4-1-2-6(10)5(3-4)7(9)11/h1-3,10H,(H2,9,11)

InChIKey

NNHMQZBVJPQCAK-UHFFFAOYSA-N

LogP

1.1444999999999999

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

163

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

NSC-407139
Benzamide, 5-chloro-2-hydroxy-
5-Chloro-2-hydroxy-benzamide
SCHEMBL552216
NSC 407139
SY020990
W10549
5chloro-2-hydroxy-benzamide
FT-0620252
EN300-17768
5-chlorosalicyl-amide
C0787
5-Chloro-2-hydroxybenzamide
NSC407139
5-chloro salicylamide
FS-3148
5-chloranyl-2-oxidanyl-benzamide
DTXSID40324590
MFCD00007980
AKOS000207652
EC 620-735-6
AM804264
Z57032581
InChI=1/C7H6ClNO2/c8-4-1-2-6(10)5(3-4)7(9)11/h1-3,10H,(H2,9,11
7120-43-6
CHEMBL1940495
CS-W017643
AC-18517
5-Chlorosalicylamide
5-Chloro-2-hydroxybenzamide #
NS00006351

MDL Number

MFCD00007980

Customs Code

2924299090

FAQ

What regulatory guidelines apply to 5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6)?

5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6) is classified under the Globally Harmonized System of Classification and Labeling of Chemicals (GHS) as a skin and eye irritant. It falls under the European Union's REACH regulation, requiring manufacturers and importers to register substances above 1 tonne per year. FDA and EPA regulations may also apply for its use in pharmaceuticals and environmental impact assessments, respectively.

Are there alternatives to 5-Chloro-2-hydroxybenzamide in synthesis?

Yes, there are alternatives to 5-Chloro-2-hydroxybenzamide in synthesis, such as 5-Amino-2-hydroxybenzamide and 5-Chloro-2-hydroxybenzoic acid. These alternatives may offer different reactivity and can be used as more environmentally friendly or cost-effective options depending on the specific application.

What is the market or research trend for 5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6)?

The market for 5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6) is growing due to its use in pharmaceuticals and as a precursor in the synthesis of other chemicals. Research trends include its application in anti-inflammatory and antifungal drug development. The demand is driven by increasing drug discovery efforts and advancements in the healthcare industry.

How should waste containing 5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6) be handled?

Waste containing 5-Chloro-2-hydroxybenzamide (CAS: 7120-43-6) should be collected in sealed containers and disposed of in accordance with local and national regulations. Incineration is a common disposal method, but professional waste disposal services should be used for handling larger volumes. Environmental protection measures include ensuring no waste leaks into groundwater and proper ventilation during handling to avoid inhalation risks.