1-(3-Amino-2-hydroxyphenyl)ethanone

Basic Information

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CAS Number

70977-72-9

Molecular Formula

C8H9NO2

Molecular Weight

151.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

93-96°C

Boiling Point

287.2°C at 760 mmHg

SMILES

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CC(=O)c1cccc(N)c1O

InChI

InChI=1S/C8H9NO2/c1-5(10)6-3-2-4-7(9)8(6)11/h2-4,11H,9H2,1H3

InChIKey

NLLYXOVHEQVWJF-UHFFFAOYSA-N

LogP

1.1769999999999998

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

158

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-(3-Amino-2-hydroxyphenyl)ethanone
3-Amino-2-Hydroxy Acetophenone 3'-Amino-2'-Hydroxy Acetophenone
Ethanone, 1-(3-amino-2-hydroxyphenyl)- (9CI)
3amino-2hydroxyacetophenone (intermediate of pranlukast)
3-Amino-2-hydroxyacetophenone
2'-Hydroxy-3'-aminoacetophenone
1-(3-aMinophenyl)-2-hydroxyethan-1-one
Ethanone, 1-(3-aMino-2-hydroxyphenyl)-
3'-Amino-2'-hydroxyacetophenone
Acetophenone,3'-amino-2'-hydroxy- (7CI)
2-Acetyl-6-aminophenol
3-Amino-2-hydroxy acetophenone
1-(3-amino-2-hydroxyphenyl)ethan-1-one
1-(3-amino-2-hydroxy-phenyl)ethanone
1-(3-amino-2-hydroxy-phenyl)-ethanone
PubChem10346
3-AminoC2-Hydroxy Acetophenone
NLLYXOVHEQVWJF-UHFFFAOYSA-N
s486

MDL Number

MFCD03428566

Customs Code

2922509090

FAQ

What is 1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9)?

1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) is an organic compound with the chemical formula C8H10N2O2. It contains a ketone group and a substituted phenyl ring with both amino and hydroxy functionalities, making it a versatile building block in chemical synthesis. The compound is typically used as an intermediate in pharmaceutical and industrial applications due to its reactivity and structural adaptability.

What are the main uses of 1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9)?

1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) is primarily used in pharmaceutical research as a precursor for drug development, particularly in compounds targeting metabolic disorders. It also serves in industrial processes for synthesizing dyes, polymers, and other organic materials. Additionally, it is employed in chemical research to create derivatives with modified functional groups for specialized applications.

Is 1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) safe?

1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) is generally considered low toxicity when handled properly, but standard safety precautions should be followed. It may cause skin or eye irritation, so protective gloves, goggles, and ventilation are recommended. Always refer to the Safety Data Sheet (SDS) for specific handling guidelines and regulatory compliance.

How should 1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) be stored?

1-(3-Amino-2-hydroxyphenyl)ethanone (CAS: 70977-72-9) should be stored in a cool, dry, and dark place to maintain stability. Keep it in a sealed container at 2-8°C to prevent moisture absorption and degradation. Avoid exposure to air and light, and ensure proper labeling for safe handling and storage.