2-Amino-5-bromonicotinonitrile

Basic Information

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CAS Number

709652-82-4

Molecular Formula

C6H4BrN3

Molecular Weight

187.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

286.1°C at 760 mmHg

Density

1.8

Flash Point

126.8℃

Refractive Index

1.66

SMILES

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C1=C(C=NC(=C1C#N)N)Br

InChI

InChI=1S/C6H4BrN3/c7-5-1-4(2-8)6(9)10-3-5/h1,3H,(H2,9,10)

InChIKey

UJKZMLZIIIGCMI-UHFFFAOYSA-N

LogP

1.73472

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

162

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Amino-5-bromo-nicotinonitrile
EN300-117896
UJKZMLZIIIGCMI-UHFFFAOYSA-N
AKOS006288796
2-AMINO-5-BROMONICOTINONITRILE
2-amino-5-bromo-pyridine-3-carbonitrile
MFCD08688591
BP-21317
AC-25636
2-amino-5-bromopyridine-3-carbonitrile
SY018088
AB48207
CS-W015659
709652-82-4
AM20061740
Z1198180781
2-Amino-5-bromo-3-pyridinecarbonitrile
J-507915
SCHEMBL322329
DTXSID90640090
5-bromo-3-cyano-2-aminopyridine
A9326
2-Amino-5-bromo-3-cyanopyridine
BCP11338
FS-2823
2-Amino-5-bromo-nicotinonitrile, AldrichCPR
FT-0645311
2-Amino-5-bromonicotinonitrile
2-Amino-5-bromopyridine-3-carbonitrile
3-Pyridinecarbonitrile,2-amino-5-bromo-

MDL Number

MFCD08688591

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4)?

2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4) is a crystalline solid with a molecular weight of approximately 230.02 g/mol. It is slightly soluble in water and has good solubility in organic solvents such as ethanol and acetone. It exhibits high reactivity towards nucleophiles due to the presence of the amino and bromine substituents.

How is 2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4) typically synthesized?

2-Amino-5-bromonicotinonitrile is typically synthesized via the bromination of 2-cyanonicotinonitrile followed by the amination of the resulting bromo compound. The reaction is catalyzed by a Lewis acid such as aluminum bromide and proceeds with good selectivity and yield.

What industries use 2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4)?

2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4) is used in the pharmaceutical industry for the synthesis of certain medicinal compounds. It is also utilized in the polymer industry for the development of new materials and in the electronics sector for the fabrication of semiconductor devices.

What precautions should be taken when handling 2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4)?

When handling 2-Amino-5-bromonicotinonitrile (CAS: 709652-82-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately and handled according to the Material Safety Data Sheet (MSDS/SDS).