Metixene hydrochloride hydrate

Basic Information

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CAS Number

7081-40-5

Molecular Formula

C20H26ClNOS

Molecular Weight

363.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

215-217°

Boiling Point

419.7°C at 760 mmHg

Flash Point

419.7 °C at 760 mmHg

SMILES

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CN1CCCC(C1)CC2C3=CC=CC=C3SC4=CC=CC=C24.O.Cl

InChI

InChI=1S/C20H23NS.ClH.H2O/c1-21-12-6-7-15(14-21)13-18-16-8-2-4-10-19(16)22-20-11-5-3-9-17(18)20;;/h2-5,8-11,15,18H,6-7,12-14H2,1H3;1H;1H2

InChIKey

RAOHHYUBMJLHNC-UHFFFAOYSA-N

LogP

4.612100000000006

Topological Polar Surface Area

34.74 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

349

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-0085190
Methixene hydrochloride hydrate
Trest (TN)
D01871
Methixene hydrochloride anhydrous
1-Methyl-3-[(9H-thioxanthen-9-yl)methyl]piperidine--hydrogen chloride--water (1/1/1)
FT-0657024
METIXENE HYDROCHLORIDE [EP MONOGRAPH]
Trest
Metixene hydrochloride anhydrous
Methixene hydrochloride monohydrate
EINECS 216-300-1
METHIXENE HYDROCHLORIDE [ORANGE BOOK]
Contalyl
3-((9H-Thioxanthen-9-yl)methyl)-1-methylpiperidinehydrochloridehydrate
NSC 78194
Metixene Hydrochloride; (RS)-1-methyl-3-[(9H-thioxanthen-9-yl)methyl]piperidine hydrochloride
1-methyl-3-(9H-thioxanthen-9-ylmethyl)piperidine;hydrate;hydrochloride
MLS002153842
NSC-78194
METIXENE HYDROCHLORIDE [MART.]
Methixene hydrochloride (USAN)
SCHEMBL121381
3-hydroxy-2-(4-methoxyphenyl)chromen-4-one;3-((9H-Thioxanthen-9-yl)methyl)-1-methylpiperidine hydrochloride hydrate
Methixene hydrochloride [USAN]
METIXENE HYDROCHLORIDE (MART.)
CHEBI:51025
METIXENE HYDROCHLORIDE (EP IMPURITY)
7081-40-5
METIXENE HYDROCHLORIDE [EP IMPURITY]
Piperidine, 1-methyl-3-(thioxanthen-9-ylmethyl)-, hydrochloride

MDL Number

MFCD00941488

Customs Code

2934999090

FAQ

What is Metixene hydrochloride hydrate (CAS: 7081-40-5)?

Metixene hydrochloride hydrate is a pharmaceutical compound with the CAS number 7081-40-5. It is a hydrate form of metixene hydrochloride, which is an antihistamine used in allergy treatments. It has a chemical structure that includes a tetrahydroisoquinoline ring system, and its hydrate form enhances its stability and solubility.

What are the main uses of Metixene hydrochloride hydrate (CAS: 7081-40-5)?

Metixene hydrochloride hydrate is primarily used in the treatment of allergic rhinitis and urticaria. It is an antihistamine that helps relieve symptoms such as itching, sneezing, and runny nose. This compound is also used in veterinary medicine for similar purposes, such as managing allergic reactions in pets.

Is Metixene hydrochloride hydrate (CAS: 7081-40-5) safe?

Metixene hydrochloride hydrate is generally considered safe when used as directed. However, it may cause side effects such as drowsiness, dizziness, or dry mouth. It is important to follow the dosage instructions and medical advice to minimize risk. Always wear gloves when handling the compound and avoid contact with eyes and skin. In case of accidental ingestion, seek medical attention immediately.

How should Metixene hydrochloride hydrate (CAS: 7081-40-5) be stored?

Metixene hydrochloride hydrate should be stored in a cool, dry place, away from direct sunlight and moisture. It is recommended to keep the compound in a tightly sealed container at room temperature (15-30°C or 59-86°F) to maintain its stability and potency. Avoid storing it in humid areas or high temperatures, as this can degrade the compound over time.