6-Bromopyrazolo[1,5-a]pyrimidine

Basic Information

View in Editor

CAS Number

705263-10-1

Molecular Formula

C6H4BrN3

Molecular Weight

198.02 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

122-124 °C

Density

1.891

Water Solubility

Slightly soluble in water.

Refractive Index

1.751

SMILES

View in Editor

C1=C2N=CC(=CN2N=C1)Br

InChI

InChI=1S/C6H4BrN3/c7-5-3-8-6-1-2-9-10(6)4-5/h1-4H

InChIKey

VDHTXLUCUNPVLO-UHFFFAOYSA-N

LogP

1.4917999999999993

Topological Polar Surface Area

30.19 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

130

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Light Sensitive

Synonyms & References

English

CS-M2471
SS-4574
A9300
6-Bromo-pyrazolo[1,5-a]pyrimidine
AM20100668
SCHEMBL1564698
FT-0684622
J-518452
Z489928452
VDHTXLUCUNPVLO-UHFFFAOYSA-N
MFCD09832894
DTXSID40623651
BCP08936
PYRAZOLO[1,5-A]PYRIMIDINE, 6-BROMO-
AKOS010006704
6-BROMOPYRAZOLO[1,5-A]PYRIMIDINE
SY020283
705263-10-1
EN300-45241
PB23680
6-Bromopyrazolo(1,5-a)pyrimidine
6-Bromopyrazolo[1,5-a]pyrimidine
6-bromopyrazolo(1,5-a)pyrimidine
RW3024
PubChem15248
STL415170
RP08696
BC003993
AB1004497
ST1261409
A

MDL Number

MFCD09832894

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Bromopyrazolo[1,5-a]pyrimidine (CAS: 705263-10-1)?

6-Bromopyrazolo[1,5-a]pyrimidine is a crystalline solid with a molecular weight of approximately 244.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMF and DMSO. The compound is moderately reactive, particularly with nucleophiles. It can form stable complexes with metal ions.

How is 6-Bromopyrazolo[1,5-a]pyrimidine (CAS: 705263-10-1) typically synthesized?

6-Bromopyrazolo[1,5-a]pyrimidine is commonly synthesized via the bromination of pyrazolo[1,5-a]pyrimidine using N-bromosuccinimide (NBS) as the brominating agent. The reaction is typically performed in the presence of a suitable solvent such as dichloromethane or acetonitrile under light or heat. The yield is usually moderate to good, around 70-80%.

What industries use 6-Bromopyrazolo[1,5-a]pyrimidine (CAS: 705263-10-1)?

6-Bromopyrazolo[1,5-a]pyrimidine is used in the pharmaceutical industry for its potential as a drug candidate. It also finds applications in the polymer industry as a monomer for the development of new materials. Additionally, it is utilized in sensor technology and as a precursor in semiconductor manufacturing.

What precautions should be taken when handling 6-Bromopyrazolo[1,5-a]pyrimidine (CAS: 705263-10-1)?

When handling 6-Bromopyrazolo[1,5-a]pyrimidine, it is important to use appropriate personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation of the compound. In case of a spill, it should be carefully cleaned up using appropriate methods, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.