1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid | CAS No. 70459-04-0
1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Basic Information
CAS Number
70459-04-0
Molecular Formula
C17H18FN3O4
Molecular Weight
347.35 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
292-293 ºC (methanol )
Density
1.453±0.06 g/cm3 (20 ºC 760 Torr),
Synonyms & References
English
- CHEBI:186132
- 70459-04-0
- N-Formylnorfloxacin
- 4-N-Formyl-1-Piperazinyl-Norfloxacin
- 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-1,4-dihydro-4-oxo-
- 1-ethyl-6-luoro-7-(4-ormylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
- Norfloxacin EP Impurity G
- N-Formyl Norfloxacin
- H447VL6G86
- A900347
- 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
- 1-ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
- UNII-H447VL6G86
- SCHEMBL9551557
- 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid;_x000b_1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Norfloxacin impurity G
- DTXSID701315594
- N-Formylnorfloxacin (M42)
- 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
- 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline- 3-carboxylic acid
- 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; Norfloxacin Imp. G (EP); Norfloxacin Impurity G
- Norfloxacin impurity G [EP IMPURITY]
- 7-(4-formylpiperazin-1-yl)-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- CHEMBL740
- Imp. G (EP): 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid
- 1-ethyl-6<wbr>
- 3-quinoli<wbr>
- LogP
- 1-Ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
- Norfloxacin Impurity G(EP)
- 1-ethyl-6-fluoro-7-(4-formylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
MDL Number
MFCD27967091
FAQ
What are the physical and chemical properties of 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0)?
1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0) is a crystalline solid with a molecular weight of approximately 338.19 g/mol. It is moderately soluble in water and has good solubility in organic solvents. This compound exhibits moderate reactivity, particularly towards nucleophiles. Its physical properties include a melting point of 150-152°C and a density of 1.34 g/cm³.
How is 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0) typically synthesized?
This compound is synthesized via a multi-step process involving the condensation of 6-fluoro-7-hydroxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid with 1-ethyl-4-formylpiperazine. The reaction typically requires the use of a base like triethylamine and is carried out in an inert atmosphere. The product is isolated via crystallization from a suitable solvent, with a yield of approximately 75-80%.
What industries use 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0)?
1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0) is primarily used in the pharmaceutical industry for the development of novel drugs. It is also explored in the sensor and semiconductor industries for its unique chemical properties and potential applications.
What precautions should be taken when handling 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0)?
When handling 1-Ethyl-6-fluoro-7-(4-formyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 70459-04-0), ensure the use of personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated fume hood to minimize exposure to vapors. Follow standard laboratory safety protocols, and have a spill kit and emergency response plan in place. Refer to the Safety Data Sheet (SDS) for more detailed information on handling and disposal.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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