6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide

Basic Information

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CAS Number

70374-39-9

Molecular Formula

C13H10ClN3O4S2

Molecular Weight

371.83 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

230°C(dec.)

Boiling Point

No data available

Density

1.727

Flash Point

No data available

Solubility

DMSO: >5mg/mL (warmed)

Refractive Index

1.741

SMILES

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CN1C(=C(C2=C(S1(=O)=O)C=C(S2)Cl)O)C(=O)NC3=CC=CC=N3

InChI

InChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)

InChIKey

WLHQHAUOOXYABV-UHFFFAOYSA-N

LogP

2.2959000000000005

pKa

pKa2 4.7(at 25℃)

Topological Polar Surface Area

99.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

634

Safety Information

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GHS Hazard Pictograms

H300

Hazard Statement

H300 Fatal if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

thermally sensitive

Toxicity

LD50 orally in mice, rats, rabbits, dogs, monkeys: >10 mg/kg (Pruss)

Synonyms & References

English

E?-thieno[2,3-e][1,2]thiazine-3-carboxamide
6-Chloro-4-hydroxy-2-methyl-N-2-pyridyl-2H-thieno(2,3-e)-1,2-thiazine-3-carboxamide 1,1-dioxide
6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (Lornoxicam)
AB00876293_06
6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1lambda6-thieno[2,3-e][1,2]thiazine-3-carboxamide
MFCD00866163
MLS001165721
NS00004372
SCHEMBL35101
NSC759620
70374-39-9
Telos
(3Z)-6-chloranyl-2-methyl-1,1-bis(oxidanylidene)-3-[oxidanyl-(pyridin-2-ylamino)methylidene]thieno[2,3-e][1,2]thiazin-4-one
6-Chloro-4-hydroxy-2-methyl-N-pyridin-2-yl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide-1,1-dioxide
C76243
6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1$l^{6},5,2-thieno[2,3-e][1$l^{6},2]thiazine-3-carboxamide
(3Z)-6-chloro-3-[hydroxy-(2-pyridinylamino)methylidene]-2-methyl-1,1-dioxo-4-thieno[2,3-e]thiazinone
SR-01000799148-3
6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-Dioxide
Q2734874
CCRIS 8589
NSC 759620
6-Chloro-4-hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-Dioxide
6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide1,1-dioxide
Pharmakon1600-01502302
AB00876293_04
Lornoxicam, >=98% (HPLC)
SCHEMBL1650239
SW220125-1
BDBM92331
BRN 1039965

MDL Number

MFCD00866163

Customs Code

2934999090

FAQ

What is 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (CAS: 70374-39-9)?

6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide is a complex organic compound with the CAS number 70374-39-9. It contains a thiazine ring fused with a thiophene and pyridine ring, and is characterized by its chloro, hydroxy, and carboxamide functional groups. This compound is known for its potential biological activity and is often studied in medicinal chemistry due to its structural complexity and functional versatility.

What are the main uses of 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (CAS: 70374-39-9)?

This compound is primarily used in pharmaceutical research as a potential lead molecule for drug development. Its unique structure suggests applications in the treatment of various diseases, including infections and inflammatory conditions. It may also find use in chemical synthesis and as an intermediate in the production of other pharmaceutical compounds, due to its reactivity and functional group diversity.

Is 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (CAS: 70374-39-9) safe?

The safety of 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide depends on its specific application and exposure conditions. As a chemical compound, it may require careful handling in laboratory settings due to its potential reactivity. Safety data suggests the need for protective measures such as gloves and goggles, and adherence to standard chemical safety protocols is recommended for safe use.

How should 6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide (CAS: 70374-39-9) be stored?

6-Chloro-4-hydroxy-2-methyl-N-(2-pyridinyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide should be stored in a cool, dry, and dark place, away from moisture and light. It is recommended to keep it in a sealed container at a temperature below 25°C to maintain stability. Proper storage conditions are essential to prevent degradation and ensure the compound remains effective for its intended applications.