Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate | CAS No. 70374-38-8

Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate

Basic Information

CAS Number

70374-38-8

Molecular Formula

C10H12ClNO6S2

Molecular Weight

341.79 g/mol

AD

Basic Physical Properties

CN(CC(=O)OC)S(=O)(=O)C1=C(SC(=C1)Cl)C(=O)OC

InChI

InChI=1S/C10H12ClNO6S2/c1-12(5-8(13)17-2)20(15,16)6-4-7(11)19-9(6)10(14)18-3/h4H,5H2,1-3H3

InChIKey

AMNIHQZRIVJTPY-UHFFFAOYSA-N

LogP

0.9815999999999997

Topological Polar Surface Area

89.98 Ų

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

477

Synonyms & References

English

  • SCHEMBL24581362
  • 5-Chloro-3-(methoxycarbonylmethylmethylsulfamoyl)thiophene-2-carboxylicacidmethylester
  • methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]thiophene-2-carboxylate
  • A836863
  • 5-CHLORO-3-(METHOXYCARBONYLMETHYLMETHYLSULFAMOYL)THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
  • Methyl 5-chloro-3-(N-(2-methoxy-2-oxoethyl)-N-methylsulfamoyl)thiophene-2-carboxylate
  • 70374-38-8
  • FT-0696001
  • 5-Chloro-3-[N-(methoxycarbonylmethyl)-N-methylsulfamoyl]-thiophene-2-carboxylic acid methyl ester
  • 5-Chloro-3-[N-(methoxy-carbonyl-methyl)sulfamoyl]-2-thiophene carboxylic acid methyl ester
  • 5-Chloro-3-[N-(Methoxycarbonylmethyl)-N-MethylSulfamoyl]-Thiophene-2-CarboxylicAicdMethylEster
  • 5-chloro-3-[N-(methoxycarbonylmethyl)-N-methylsulfanoyl]
  • 5-CHLORO-3-[N-(METHOXYCARBOOYLMCTHYL)-N-METHYLSULFAMOYL]-THIOPHENE-2-CARBOX YLATC ACID MCTHYL CSTER

MDL Number

MFCD08063924

Customs Code

2935009090

FAQ

What are the physical and chemical properties of Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8)?

Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8) is a crystalline solid with a molecular weight of approximately 375.06 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. Chemically, it is reactive towards nucleophiles and can undergo sulfonamide and thiophenecarboxylic acid-related transformations.

How is Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8) typically synthesized?

Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8) is typically synthesized through a multi-step process involving the reaction of a thiophenecarboxylic acid derivative with a sulfamoyl chloride in the presence of a base. Commonly used bases include triethylamine, and the reaction yields a high degree of selectivity and a good yield of the desired product.

What industries use Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8)?

Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8) is used in pharmaceuticals and polymers industries. It serves as a precursor in the synthesis of active pharmaceutical ingredients and can also be utilized in the development of advanced polymers with specific properties.

What precautions should be taken when handling Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8)?

When handling Methyl 5-chloro-3-[(2-methoxy-2-oxoethyl)(methyl)sulfamoyl]-2-thiophenecarboxylate (CAS: 70374-38-8), adequate personal protective equipment (PPE) such as gloves, goggles, and lab coats should be worn. It should be stored in a cool, dry place away from direct sunlight and flammable materials. In case of a spill, it is recommended to use appropriate spill kits and follow proper waste disposal procedures as outlined in the Material Safety Data Sheet (MSDS/SDS).

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