1-Methyl-D-proline hydrochloride (1:1)

Basic Information

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CAS Number

702710-17-6

Molecular Formula

C6H12ClNO2

Molecular Weight

165.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CN1CCCC1C(=O)O.Cl

InChI

InChI=1S/C6H11NO2.ClH/c1-7-4-2-3-5(7)6(8)9;/h5H,2-4H2,1H3,(H,8,9);1H/t5-;/m1./s1

InChIKey

ZHNOJJGMMVVUGM-NUBCRITNSA-N

LogP

0.587

Topological Polar Surface Area

40.540000000000006 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

124

Synonyms & References

English

N-Methyl-D-prolineHydrochloride
(2R)-1-METHYLPYRROLIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE
N-Methyl-d-proline HCl
A866637
SCHEMBL1721046
CDB71017
CS-11261
AKOS015902762
(R)-1-Methylpyrrolidine-2-carboxylic acid hydrochloride
ZHNOJJGMMVVUGM-NUBCRITNSA-N
CS-W001913
MFCD18375303
1-Methyl-D-proline HCl
(2R)-1-methylpyrrolidine-2-carboxylic acid;hydrochloride
702710-17-6
N-Methyl-D-proline Hydrochloride
N-Methyl-D-proline, HCl
(2R)-1-methylpyrrolidine-2-carboxylic acid,hydrochloride
1-methyl-D-Proline hydrochloride
N-Methyl-d-proline, HCl
KM1333
SB13704
AX8268666
V7386

MDL Number

MFCD18375303

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 1-Methyl-D-proline hydrochloride (CAS: 702710-17-6)?

1-Methyl-D-proline hydrochloride (CAS: 702710-17-6) is a crystalline solid with a molecular weight of approximately 201.66 g/mol. It has a high solubility in water and moderate solubility in organic solvents. Chemically, it is less reactive than its parent compound, D-proline, and is often used in various synthetic transformations. It exhibits good stability under normal conditions but can degrade under strongly basic conditions.

How is 1-Methyl-D-proline hydrochloride (CAS: 702710-17-6) typically synthesized?

1-Methyl-D-proline hydrochloride (CAS: 702710-17-6) is typically synthesized via the condensation of methylamine and D-proline. The reaction is performed in acidic conditions using hydrochloric acid as a catalyst. The yield is generally high, and the product is isolated by recrystallization from water or an organic solvent.

What industries use 1-Methyl-D-proline hydrochloride (CAS: 702710-17-6)?

1-Methyl-D-proline hydrochloride (CAS: 702710-17-6) is used in the pharmaceutical industry for the synthesis of certain prodrugs and in the polymer industry for the modification of polymer chains. It also has applications in the manufacturing of sensors and semiconductors due to its specific chemical properties and reactivity.

What precautions should be taken when handling 1-Methyl-D-proline hydrochloride (CAS: 702710-17-6)?

When handling 1-Methyl-D-proline hydrochloride (CAS: 702710-17-6), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to avoid inhalation. Spills should be handled with appropriate absorbent materials and disposed of according to local regulations. A safety data sheet (SDS) should be consulted for detailed information on handling and storage.