1-Benzyl-N-methyl-4-piperidinamine

Basic Information

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CAS Number

7006-50-0

Molecular Formula

C13H20N2

Molecular Weight

204.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

303.1℃ at 760 mmHg

Flash Point

126.4℃

SMILES

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CNC1CCN(CC1)CC2=CC=CC=C2

InChI

InChI=1S/C13H20N2/c1-14-13-7-9-15(10-8-13)11-12-5-3-2-4-6-12/h2-6,13-14H,7-11H2,1H3

InChIKey

RGEQSTMITLEXKD-UHFFFAOYSA-N

LogP

1.8703999999999996

Topological Polar Surface Area

15.27 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

167

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1-benzyl-4-(N-methylamino)piperidine
1-benzyl-N-methyl-piperidin-4-amine
(1-BENZYL-PIPERIDIN-4-YL)-N-METHYL-AMINE
1-benzyl-4-methylaminopiperidine
1-BENZYL-N-METHYL-4-PIPERIDINAMINE
4-methylamino-1-n-(phenylmethyl)piperidine
DB-0816
N-[1-(benzyl)-4-piperidyl]-N-methylamine
N-(1-benzylpiperidin-4-yl)-N-methylamine
4-Piperidinamine, N-methyl-1-(phenylmethyl)-
EN300-76694
CS-W015398
(1-Benzyl-piperidin-4-yl)-methyl-amine
AC-2785
SCHEMBL360075
1-benzyl-N-methylpiperidin-4-amine
4-methylamino-1-benzyl piperidine
SY002902
N-Methyl-(1-benzyl-piperidin-4-yl)amine
7006-50-0
1-benzyl-4-(methylamino)piperidine
FT-0648690
AKOS000147551
SB43365
Z102766908
1-Benzyl-4-(N-methyl)piperidinamine
A9260
N-(1-benzylpiperidin-4yl)-N-methylamine
1-benzyl-N-methylpiperidine-4-amine
DTXSID40399748
4-methylamino-1-benzylpiperidine

MDL Number

MFCD03931054

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 1-Benzyl-N-methyl-4-piperidinamine (CAS: 7006-50-0)?

1-Benzyl-N-methyl-4-piperidinamine is a white crystalline solid with a molecular weight of approximately 226.33 g/mol. It has a pKa of about 9.7 and is slightly soluble in water. The compound is reactive towards basic conditions and can undergo hydrolysis. It is also prone to oxidation and should be stored away from air and moisture.

How is 1-Benzyl-N-methyl-4-piperidinamine (CAS: 7006-50-0) typically synthesized?

1-Benzyl-N-methyl-4-piperidinamine is typically synthesized via a multi-step process. The key step involves the reaction of 4-methylpiperidine with benzyl chloride in the presence of a base such as triethylamine. The reaction is carried out in an aprotic solvent like dichloromethane. The yield and selectivity can be improved by using appropriate catalysts and reaction conditions.

What industries use 1-Benzyl-N-methyl-4-piperidinamine (CAS: 7006-50-0)?

1-Benzyl-N-methyl-4-piperidinamine finds applications in pharmaceuticals, predominantly as a precursor for drug synthesis. It is also used in the production of certain polymers and as a reagent in organic synthesis. Its use in sensors and semiconductors is limited but possible due to its functional groups.

What precautions should be taken when handling 1-Benzyl-N-methyl-4-piperidinamine (CAS: 7006-50-0)?

When handling 1-Benzyl-N-methyl-4-piperidinamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be carried out in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.