Cimetidine hydrochloride

Basic Information

View in Editor

CAS Number

70059-30-2

Molecular Formula

C10H17ClN6S

Molecular Weight

288.8 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

186-190°C

Boiling Point

488 °C at 760 mmHg

Flash Point

248.9 °C

SMILES

View in Editor

[H+].[Cl-].CN\C(NCCSCC1=C(C)NC=N1)=N\C#N

InChI

InChI=1S/C10H16N6S.ClH/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11;/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14);1H

InChIKey

QJHCNBWLPSXHBL-UHFFFAOYSA-N

LogP

2.18118

Complexity

296

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Cimetidine hydrochloride
Cimetidine HCL
3-Cyano-2-methyl-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine hydrochloride
cimetex
Cimetidine Hydrochloride USP24
Cimetidin-HCl
Cimetidinhydrochlorid

MDL Number

MFCD01724314

Customs Code

2933290090

FAQ

What regulatory guidelines apply to cimetidine hydrochloride (CAS: 70059-30-2)?

Cimetidine hydrochloride (CAS: 70059-30-2) is subject to regulatory guidelines under the Globally Harmonized System (GHS) for classification and labeling of chemicals. In the European Union, it falls under REACH regulations, requiring manufacturers and importers to register substances above a certain tonnage threshold. The U.S. FDA and EPA have specific requirements for the use and regulation of this compound in pharmaceuticals and environmental protection, respectively.

Are there alternatives to cimetidine hydrochloride (CAS: 70059-30-2) in synthesis?

Alternative compounds to cimetidine hydrochloride (CAS: 70059-30-2) in synthesis include other histamine H2 receptor antagonists such as ranitidine and famotidine. These can be used as substitutes depending on the specific application and synthesis route. Isomers and analogs may also be explored, but thorough testing is necessary to ensure efficacy and safety.

What is the market or research trend for cimetidine hydrochloride (CAS: 70059-30-2)?

The market for cimetidine hydrochloride (CAS: 70059-30-2) is primarily driven by its use as a proton pump inhibitor in treating gastrointestinal disorders. Research trends are shifting towards understanding its long-term effects and exploring potential alternative uses, such as in cancer therapy. Market analysis indicates a stable demand with a focus on safety and efficacy, particularly in light of recent regulatory challenges.

How should waste containing cimetidine hydrochloride (CAS: 70059-30-2) be handled?

Waste containing cimetidine hydrochloride (CAS: 70059-30-2) should be collected in appropriate containers and disposed of according to local and national regulations. Incineration is a common method for disposal, but professional waste disposal services are recommended for larger quantities. Environmental protection measures include ensuring no contamination of soil or water sources, and following all safety precautions during handling and disposal.